20 results about "Eye infection" patented technology

Embodiments of the present invention generally relate to novel immunostimulatory compositions of use to stimulate non-specific immune responses in a subject. In certain embodiments, immunogenic compositions disclosed herein can be directed to use in the eye of a subject. In some embodiments, the immunogenic compositions disclosed herein enhance non-specific immune responses in the eye of a subject to treat or reduce the risk of onset of an eye condition. In other embodiments, compositions disclosed herein can be used to treat eye infections due to a microorganism, tumors of the eye, as well as, chronic wounds or infections of the eye. In some embodiments, immunogenic ocular formulations disclosed herein include combinations of agents for prolonged exposure to the eye for improved outcomes.

The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative. The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative thereof, for use in a method for the treatment of conjunctivitis and for the prevention or treatment of inflammation or prevention of infection after cataract surgery in a subject, according to a dosage regimen that improves patient compliance and tolerability and enables the prevention and treatment of intermediate / antibiotic-resistant infections.

The present invention relates to a method for simultaneously detecting a plurality of pathogens from biologically-derived samples, and a kit for carrying out the method. Specifically, the present invention relates to a method for simultaneously detecting a plurality of pathogens that cause infectious uveitis, one of eye infections from samples such as anterior chamber fluid or vitreous by polymerase chain reaction (PCR), and a kit for carrying out the method.

A method of treating an eye disorder in a patient that may include administering a medicament to the patient with a prefilled syringe, wherein the administration of the medicament with the prefilled syringe is configured to treat the eye disorder and decrease a rate of likelihood of an ocular infection to the patient's eye.

A medicinal eye drop formulation comprising 10 mg / mL (±5%) to 25 mg / mL (±5%) Vancomycin hydrochloride or, in each case, an equivalent amount of Vancomycin free base or an equivalent amount of an alternative salt of Vancomycin, Tryptophan, Mannitol and Methylcellulose for use in treating eye infection in a human subject.

The utility model discloses an eyelid expanding and supporting type eye drop fixator which comprises a fixed handle and a rotating handle, the upper section of the fixed handle serves as a handheld part and is fixedly provided with a first grip, the middle section of the fixed handle serves as an installation part and is detachably provided with an eye drop bottle, and the lower section of the fixed handle serves as an expanding and supporting part and is movably provided with an eyelid expanding and supporting structure. The eyelid expanding and supporting structure is in mechanical linkage with the rotating handle, in the rotating process of the rotating handle, on one hand, the eyelid expanding and supporting structure can expand the eyelid of a user to ensure that the eyeball of the user is fully exposed below the dropping opening of the eyedrop bottle, and on the other hand, the eyedrop bottle can be squeezed to enable eyedrop to drop into the eyeball of the user from the dropping opening. Through the reasonable structural design, the problems of difficult operation and eye infection risk in the existing eye drop dripping process are solved. The fixing device is easy and convenient to operate, high in accuracy, high in safety and wide in application range, and a more convenient, comfortable and safe eyedrop dripping mode is provided for a patient.

The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.

The application discloses an intelligent glasses system for regulating and maintaining eyesight and a use method thereof, and relates to the technical field of smart wearable devices.The application comprises a frame and a temple, and further comprises the following modules: a main control module for processing data and coordinating the operation of each module; a line-of-sight tracking and depth estimation module for determining the eye fixation position and distance; and a posture detection module.The application realizes comprehensive monitoring and intervention of the user's eye behavior by integrating multi-modal sensors and intelligent algorithms.The system simultaneously covers eye distance regulation, bad posture recognition, electronic device usage time management and eye hygiene reminders, solves the problem of single function of the prior art, and through the line-of-sight tracking and depth estimation module, the user's position for looking near or looking far is determined in real time, and in combination with posture detection, device usage detection and eye contact detection, myopia, hyperopia, visual fatigue and eye infections and various abnormal vision conditions are prevented from multiple dimensions, and the original vision protection effect is improved.

The utility model relates to the technical field of eye massage equipment, and discloses a bone conduction atomization eye massage instrument with a disinfection effect, which comprises a massage instrument main body, temple massage assemblies are arranged at the extension sections of the two ends of the massage instrument main body, and bone conduction assemblies are arranged on the inner sides of the temple massage assemblies. The atomization assembly is arranged in the middle of the inner side of the massager body, and the eye massage assemblies are arranged on the left side and the right side of the inner side wall of the massager body. The massage instrument integrates massage, bone conduction audio frequency and atomization functions, effectively relieves eye fatigue, and provides comfortable use experience; the massage instrument has a disinfection function, ensures cleanness and sanitation of the massage instrument and reduces the risk of eye infection, particularly, the disinfection assembly adopts an advanced ultraviolet disinfection technology and can comprehensively and efficiently kill various harmful microorganisms, and the disinfection design of the ultraviolet disinfection device and the spray nozzle of the liquid storage tank and the disinfection measures of the atomizer are adopted, so that the disinfection effect is good. And the eye health of the user is jointly protected.

A subconjunctival implant and a method for treating an eye infection in an eye of a subject by placing the subconjunctival implant into a subconjunctival space of the eye. The subconjunctival implant includes an elongated body portion and a fin. At least one of the elongated body portion or the fin comprises a biocompatible polymer and a medication. The elongated body portion includes a leading edge and a trailing edge opposite the leading edge. The elongated body portion includes a dorsal surface and an anterior surface. The fin extends from the dorsal surface. The fin has a sloped leading surface extending from the dorsal surface to an apex of the fin and a trailing surface transverse to the dorsal surface and extending from the apex to the dorsal surface.

The invention belongs to the technical field of biology, and discloses a capsid protein mutant capable of improving AAV (adeno-associated virus) yield and full-eye infection ability and an application of the capsid protein mutant. The capsid protein mutant is obtained by replacing amino acids at positions 561 to 588 of wild-type AAV2 virus capsid protein with a specific polypeptide. The capsid protein mutants of some examples of the invention can effectively improve the AAV2 full-eye infection ability and fundamentally solve the problem of AAV2 eye infection efficiency. The capsid protein mutants of some examples of the invention have better yield. The capsid protein mutants of some examples of the invention can be well applied to gene therapy of eyes or construction of an eye disease model.

The application discloses a pathogen detection primer group, a kit and application in pathogen detection of eye infection, the detection primer group contains 162 pairs of primers for 54 pathogenic microorganisms, interference competition between each primer is small, and one pair of primers is selected for each pathogenic microorganism, so that the detection of the 54 pathogenic microorganisms can be realized simultaneously, when all the 162 pairs of primers are selected, the sensitivity and specificity of species identification can be improved, specific identification to species and high-sensitivity detection of bacteria, fungi, viruses and parasites can be realized, and the requirement of precise clinical diagnosis can be met.

The present disclosure provides a method of identifying and / or quantifying a perceived immune fitness of an individual. The method comprises identifying a frequency and / or a severity of one or more conditions experienced by an individual. The one or more conditions includes sore throat, headaches, flu, runny nose, coughing, cold sores, boils, mild fever, warts, pneumonia, bronchitis, sinusitis, sudden high fever, ear infection, diarrhea, meningitis, eye infection, sepsis, long healing injuries, shortness of breath, skin problems, muscle and joint pain, and common cold. The method further includes calculating a perceived immune fitness score of the individual based on up to 10 of the one or more conditions with the highest frequency and / or severity.

To provide an ophthalmic system capable of surely preventing nosocomial infection such as ophthalmic infectious disease.SOLUTION: The ophthalmic system 1 includes a face image capture device 10 installed at a hospital entrance and an terminal 20 installed in the hospital. The face imaging device 10 includes an imaging unit 11 that captures a face image Q of a patient P, a detection unit 12 that detects a sign of an eye disorder from the face image Q, a communication unit 14 that transmits and receives information to and from the terminal 20, and an instruction notification unit 15 that notifies the patient P of an instruction S from the terminal 20. The communication unit 14 transmits the face image Q to the terminal 20 at least when there is a sign of an eye disorder. When the presence or absence of an eye disorder is determined on the terminal 20 side, the instruction S is transmitted to the instruction notification unit 15, and the instruction notification unit 15 notifies the patient P of an action based on the instruction S.SELECTED DRAWING: Figure 3

A non-contact optical measuring ruler for eyes comprises a light source, a convex lens is arranged on one side of the light source, a first shading plate is arranged between one side of the convex lens and the light source, a strip-shaped measuring hole and a positioning light slit are arranged horizontally on the shading plate, a strip-shaped shading sheet is arranged on the first shading plate, the shading sheet is arranged on the measuring hole and relatively movably cooperates with the first shading plate, a measuring light slit is arranged on the shading sheet, a second shading plate is arranged on the other side of the convex lens, two splitting holes are arranged longitudinally on the second shading plate, and the positions of the two splitting holes and the measuring hole and the positioning light slit are arranged perpendicular to each other. The present invention adopts the optical imaging principle to project optical measurement marks on the measured object to complete the comparison measurement of the same plane, and its purpose is to complete the measurement of the eye structure in a non-contact state, reduce the stimulation to the eye of the examinee, and eliminate the risk of damaging the eye structure and causing eye infection caused by contact measurement.

The intelligent visual training instrument comprises a glasses box body, a charging port is formed in the outer side of the glasses box body, a display screen is arranged at the top of the glasses box body, control keys are arranged at the top of the glasses box body, an opening and closing assembly is arranged on the outer side of the glasses box body, and a training instrument assembly is arranged in the glasses box body. According to the intelligent visual training instrument, a non-invasive physical training mode is adopted, injection, medicine taking and eyeball contact are avoided, the eye infection risk possibly caused by an orthokeratology lens and complications such as xerophthalmia and visual decline possibly caused by a laser operation are avoided, and the visual training effect is improved by simulating the state of seeing far and near. According to the device, the ciliary body, the vitreous body and the crystalline lens of the eye are frequently zoomed at the same time, the elasticity of the ciliary muscle is effectively recovered, the device can be quickly charged through a universal mobile phone charger, the problem that charging is inconvenient is solved, the mute design of the double built-in stepping motors enables a user to train in a quiet environment, and the use experience is further improved.

The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.

The invention relates to the field of ophthalmology, in particular to an interesting child eye examination microscope which comprises a bottom plate. The bottom plate is fixedly connected with inspection equipment; two electric guide rails are fixedly connected to the bottom plate; the sliding blocks of the two electric guide rails are jointly connected with a fixing plate in a sliding mode. The eye area of a child is covered through the covering cover, mutual interference between ambient light in a room and detection light emitted by the observation mirror is avoided, the light of the observation mirror is shielded through the light shielding plate with the light transmittance being%, the child is under slight illumination when not being examined, adaptability is improved, and the safety of the child is improved. The problem that eyes are hurt due to the fact that strong light continuously irradiates the eyes is avoided, and meanwhile the problem that negative emotion is caused due to the fact that the eyes are uncomfortable due to sudden brightening when lamplight is turned on and turned off is avoided; and dust and impurities on the surface of the shading plate are blown away and discharged into an external collecting barrel through an exhaust pipe, so that the cleanliness of the shading plate is improved, eye infection of children is avoided, and the service life of the shading plate is prolonged.

The application discloses a capsid protein mutant capable of improving the whole-eye infection ability of an AAV virus and an application thereof. The inventors have found that the whole-eye infection ability of an AAV virus can be effectively improved by using a specific peptide to replace amino acids at positions 561 to 588 of a wild-type AAV2 virus capsid protein, and the problem of the infection efficiency of AAV2 on eyes is fundamentally solved.

The invention discloses a primer probe combination for simultaneously detecting AMB, VZV and HSV-1 as well as a detection method, application and a product of the primer probe combination, and belongs to the technical field of molecular biological detection. The technical problems to be solved are that an existing eye infection detection technology cannot synchronously detect AMB, VZV and HSV-1 in a single tube, or only covers viruses and misses AMB, or needs multi-tube operation, is fuzzy in identification, insufficient in sensitivity, difficult to adapt to eye trace samples, and cannot meet clinical rapid and accurate diagnosis requirements. According to the technical scheme, the method is characterized in that specific primer probes aiming at 18S rRNA genes of AMB, ORF62 genes of VZV and UL30 genes of HSV-1 are provided and matched with internal quality control primer probes, four different fluorescence labels are adopted, a single-tube multiple real-time fluorescent PCR detection method is established, a matched kit is prepared, and synchronous detection and identification of three pathogens are achieved. The kit is high in sensitivity and strong in specificity and anti-interference capability.