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Medication for treating primary disease of purpura haemorhagica and preparation method

A platelet, primary technology, applied in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of ITP patients without immune regulation, clinical application limited by economic reasons, and inconvenient for patients to use. , to achieve the effect of regulating immune function, improving bleeding tendency, and increasing peripheral blood platelets

Inactive Publication Date: 2005-01-12
陕西郝其军制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (1) Although it can promote the active production of platelets in the bone marrow; it is suitable for thrombocytopenia caused by bone marrow hypoproliferative diseases; but it has no immune regulation effect on ITP patients, and has no effect on antibody production;
[0005] (2), injection medication, inconvenient for patients to use;
[0006] (3), the price is expensive, and the clinical application is limited by economic reasons;
[0007] (4) Biological agents, allergic phenomena often occur, side effects such as edema, headache, fever, palpitations, tachycardia, atrial fibrillation, nausea, vomiting, dizziness, insomnia, dyspnea, rash, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0124] Weigh the raw materials according to the following ratio:

[0125] Indigo Daisy 167g Peony Bark 833g Forsythia 500g

[0126] Agrimony 500g Licorice 250g

[0127] Described dosage form is the processing step of the preparation method of capsule as follows:

[0128] (1), sieve the Qingdai fine powder, set aside;

[0129] (2), Agrimony and Cortex Moutan are extracted twice with 5 times the amount of 80% ethanol, each time for 2 hours, the ethanol extracts are combined twice, filtered, and the ethanol is recovered and concentrated under reduced pressure to a relative density at 60 ° C. 1.25-1.30 extract, set aside;

[0130] (3), soak the forsythia for 4 hours, extract the volatile oil by steam distillation for 6 hours, store the volatile oil in another container, and keep the medicinal residue and decoction for later use;

[0131](4), the dregs of step (3) and Radix Glycyrrhizae decoction are extracted 2 times, decocted for 1.5 hours each time, twice the decoction is co...

specific Embodiment 2

[0133] Weigh the raw materials according to the following ratio:

[0134] Indigo Daisy 150g Peony Bark 800g Forsythia 600g

[0135] Agrimony 600g Licorice 300g

[0136] Described dosage form is the processing step of the preparation method of granule as follows:

[0137] (1), sieve the Qingdai fine powder, set aside;

[0138] (2), Agrimony and Cortex Moutan are extracted twice with 5 times the amount of 80% ethanol, each time for 2 hours, the ethanol extracts are combined twice, filtered, and the ethanol is recovered and concentrated under reduced pressure to a relative density at 60 ° C. 1.25-1.30 extract, set aside;

[0139] (3), soak the forsythia for 4 hours, extract the volatile oil by steam distillation for 6 hours, store the volatile oil in another container, and keep the medicinal residue and decoction for later use;

[0140] (4), the dregs of step (3) and Radix Glycyrrhizae decoction are extracted 2 times, decocted for 1.5 hours each time, twice the decoction is c...

specific Embodiment 3

[0144] Weigh the raw materials according to the following ratio:

[0145] Qingdai 200g Peony bark 700g Forsythia 450g

[0146] Agrimony 450g Licorice 350g

[0147] Described dosage form is the processing step of the preparation method of tablet as follows

[0148] (1), grind Qingdai into fine powder, set aside;

[0149] (2), Agrimony and Cortex Moutan are extracted twice with 5 times the amount of 80% ethanol, each time for 2 hours, the ethanol extracts are combined twice, filtered, and the ethanol is recovered and concentrated under reduced pressure to a relative density at 60 ° C. 1.25-1.30 extract, set aside;

[0150] (3), soak the forsythia for 4 hours, extract the volatile oil by steam distillation for 6 hours, store the volatile oil in another container, and keep the medicinal residue and decoction for later use;

[0151] (4), the dregs of step (3) and Radix Glycyrrhizae decoction are extracted 2 times, decocted for 1.5 hours each time, twice the decoction is combine...

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PUM

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Abstract

A Chinese medicine for treating the primary thrombopenic purpura is prepared from 5 Chinese-medicinal materials including natural indigo, forsythia fruit, tree peony bark, liquorice root, etc. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to a medicine for treating idiopathic thrombocytopenic purpura, specifically a Chinese patent medicine prepared from traditional Chinese medicines, and also relates to a preparation method of the medicine. technical background: [0002] Idiopathic thrombocytopenic purpura (ITP) is a common clinical acquired autoimmune blood disease, the main features are thrombocytopenia and skin and mucous membrane bleeding. Its annual incidence rate is about 4.8 per 100,000 people, and the incidence rate of children is higher than that of adults. In recent years, the number of elderly patients has an increasing trend. The clinical features of ITP are different between children and adults. The former has a more acute onset, more severe symptoms, and generally responds better to treatment, while the latter has a slower onset, poor response to treatment, and some are refractory. [0003] At present, the drug treatment of this disease at home and ...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K9/20A61K9/48A61P7/04
Inventor 郝其军
Owner 陕西郝其军制药股份有限公司
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