American ginseng and its extract oral disintegration tablet and its preparing process

A technology of American ginseng extract and American ginseng, which is applied in the field of American ginseng and its extract orally disintegrating tablets and its preparation technology, which can solve the problems that the orally disintegrating tablet preparation has not been found yet

Inactive Publication Date: 2005-03-02
COSCI MED TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Orally disintegrating tablet preparations or related literature of American ginseng and its extracts have not been found

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment one direct flavoring method

[0045] 1. Prescription

[0046] 1. Raw material - American ginseng 500.0g;

[0047] 2. Filling agent - mannitol 156.0g;

[0048] Microcrystalline cellulose 56.0g;

[0049] 3. Flavoring agent—aspartame 8.0g;

[0050] 4. Disintegrant—cross-linked polyvinylpyrrolidone 34.0g;

[0051] Croscarmellose sodium 30.0g;

[0052] 5. Glidant—micronized silica gel 8.0g;

[0053] 6. Lubricant—sodium stearyl fumarate 8.0 g.

[0054] The total weight is 800g, and a total of 1000 pieces are made.

[0055] 2. Preparation method

[0056] 1) Pulverize American ginseng, pass through an 80-mesh sieve, dry, and set aside;

[0057] 2) Cross-linked polyvinylpyrrolidone, cross-linked sodium carboxymethyl cellulose, micropowder silica gel, sodium stearyl fumarate and aspartame were respectively passed through a 40-mesh sieve, mixed evenly, and then pulverized American ginseng powder was added, Mix well and set aside;

[0058] 3) add mannitol and ...

Embodiment 2

[0060] Example 2 Powder coating taste masking method

[0061] 1. Prescription

[0062] 1. Raw materials - American ginseng extract 200.0g;

[0063] 2. Coating material - Eudragit  E100 20.0g;

[0064] 3. Filling agent - mannitol 161.0g;

[0065] 4. Flavoring agent—aspartame 5.0g;

[0066] 5. Disintegrant—cross-linked polyvinylpyrrolidone 34.0g;

[0067] Croscarmellose sodium 16.0g;

[0068] 6. Glidant - micronized silica gel 9.0g;

[0069] 7. Lubricant—sodium stearyl fumarate 5.0 g.

[0070] The total weight is 450g, and a total of 1000 pieces are made.

[0071] 2. Preparation method

[0072] 1) Take Eudragit  E100 is dissolved with more than 95% pharmaceutical industrial ethanol and diluted to a certain concentration for later use;

[0073] 2) Take the American ginseng extract and boil it in a fluidized bed, spray the above solution at a certain speed for powder coating, and prepare the American ginseng and its extract powder-coated granules, and dry them for lat...

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PUM

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Abstract

The present invention relates to oral disintegrated tablet of American ginseng and its extract for treating vital energy deficiency, Yin deficiency, dyspneic cough, blood trace found in phlegm, etc. American ginseng and its extract as main material as well as stuffing, disintegrating agent, corrective, flow assistant, lubricant and other supplementary material are prepared into the oral disintegrated tablet. Into the supplementary material, adhesive, coating material and / or effervescent agent may be added, if necessary. The oral disintegrated tablet of the present invention has excellent crushing degree, fast disintegration, good taste and low cost, and may be taken with no water and high curative effect.

Description

[technical field] [0001] The invention relates to a preparation of American ginseng and its extract, which has the functions of invigorating qi and nourishing yin, clearing heat and promoting body fluid, and is used for qi deficiency and yin deficiency, internal heat, coughing and phlegm and blood, deficiency heat and tiredness, thirst and dry mouth and throat. An orally disintegrating tablet preparation of American ginseng and its extract with rapid release. [Background technique] [0002] American ginseng, also known as American ginseng, is the dried root of the Araliaceae plant American ginseng (panax guingne folium L.). The wild ones can be called "wild ginseng" or "wild ginseng", and the cultivated ones can be called "species ginseng" or "species ginseng". It is a precious tonic medicine with special medical value. [0003] American ginseng was originally wild in the jungles of North America along the Atlantic coast. It belongs to the same Araliaceae family as Chinese ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P1/02A61P11/04A61P11/14A61P25/00A61P31/04
Inventor 蒋海松王红喜王锦刚
Owner COSCI MED TECH CO LTD
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