American ginseng and its extract oral disintegration tablet and its preparing process
A technology of American ginseng extract and American ginseng, which is applied in the field of American ginseng and its extract orally disintegrating tablets and its preparation technology, which can solve the problems that the orally disintegrating tablet preparation has not been found yet
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Embodiment 1
[0044] Embodiment one direct flavoring method
[0045] 1. Prescription
[0046] 1. Raw material - American ginseng 500.0g;
[0047] 2. Filling agent - mannitol 156.0g;
[0048] Microcrystalline cellulose 56.0g;
[0049] 3. Flavoring agent—aspartame 8.0g;
[0050] 4. Disintegrant—cross-linked polyvinylpyrrolidone 34.0g;
[0051] Croscarmellose sodium 30.0g;
[0052] 5. Glidant—micronized silica gel 8.0g;
[0053] 6. Lubricant—sodium stearyl fumarate 8.0 g.
[0054] The total weight is 800g, and a total of 1000 pieces are made.
[0055] 2. Preparation method
[0056] 1) Pulverize American ginseng, pass through an 80-mesh sieve, dry, and set aside;
[0057] 2) Cross-linked polyvinylpyrrolidone, cross-linked sodium carboxymethyl cellulose, micropowder silica gel, sodium stearyl fumarate and aspartame were respectively passed through a 40-mesh sieve, mixed evenly, and then pulverized American ginseng powder was added, Mix well and set aside;
[0058] 3) add mannitol and ...
Embodiment 2
[0060] Example 2 Powder coating taste masking method
[0061] 1. Prescription
[0062] 1. Raw materials - American ginseng extract 200.0g;
[0063] 2. Coating material - Eudragit E100 20.0g;
[0064] 3. Filling agent - mannitol 161.0g;
[0065] 4. Flavoring agent—aspartame 5.0g;
[0066] 5. Disintegrant—cross-linked polyvinylpyrrolidone 34.0g;
[0067] Croscarmellose sodium 16.0g;
[0068] 6. Glidant - micronized silica gel 9.0g;
[0069] 7. Lubricant—sodium stearyl fumarate 5.0 g.
[0070] The total weight is 450g, and a total of 1000 pieces are made.
[0071] 2. Preparation method
[0072] 1) Take Eudragit E100 is dissolved with more than 95% pharmaceutical industrial ethanol and diluted to a certain concentration for later use;
[0073] 2) Take the American ginseng extract and boil it in a fluidized bed, spray the above solution at a certain speed for powder coating, and prepare the American ginseng and its extract powder-coated granules, and dry them for lat...
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