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Chinese medicine compound preparation for treating depression and its preparation method

A depression and preparation technology, applied in the field of traditional Chinese medicine, can solve the problems of patients' toxic and side effects, expensive costs, etc.

Inactive Publication Date: 2005-03-09
新疆华春生物药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Depression is a chronic disease, and most western medicines have side effects. Long-term use of the above-mentioned antidepressants not only requires expensive expenses, but also brings great toxic and side effects to patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Prescription composition:

[0037] 2000 parts by weight of Radix Pseudostellariae

[0038] Pueraria 500 parts by weight

[0039] Epimedium 100 parts by weight

[0040] Preparation Process:

[0041] Take Radix Pseudostellariae, add 12 times the amount of water (equivalent to the weight of the crude drug), soak and extract once at 95°C for 2 hours each time, filter the extract with gauze, combine the filtrates, and concentrate under reduced pressure to a relative density of about 1.19 . Add ethanol to a final concentration of 80%, let it stand overnight, and remove the supernatant. Add water to dissolve the precipitate to a density of 1.060, then add ethanol to a final concentration of 70%, let stand until no more precipitate precipitates, and remove the supernatant. Freeze-dry the precipitate to obtain the total polysaccharide;

[0042]Get Pueraria Radix and Epimedium, add 8 times the amount (equivalent to the weight of the crude drug) of 70% ethano...

Embodiment 2

[0046] Prescription composition:

[0047] 1500 parts by weight of Radix Pseudostellariae

[0048] Pueraria 1000 parts by weight

[0049] Epimedium 500 parts by weight

[0050] Preparation Process:

[0051] Take Radix Pseudostellariae, add 10 times the amount of water (equivalent to the weight of the crude drug), warm soak and extract at 90°C for 3 times, each time for 3 hours, filter the extract with gauze, combine the filtrates, concentrate under reduced pressure to a relative density of about 1.18 . Add ethanol to a final concentration of 80%, let it stand overnight, and remove the supernatant. Add water to dissolve the precipitate to a density of 1.065, then add ethanol to a final concentration of 70%, let stand until no precipitate precipitates, and remove the supernatant. Freeze-dry the precipitate to obtain the total polysaccharide;

[0052] Get Pueraria root and Epimedium leaves, add 10 times the amount (equivalent to the weight of the crude drug) ...

Embodiment 3

[0056] Prescription composition:

[0057] 1000 parts by weight of Radix Pseudostellariae

[0058] Pueraria 1500 parts by weight

[0059] Epimedium 900 parts by weight

[0060] Preparation Process:

[0061] Take Radix Pseudostellariae, add 8 times the amount of water (equivalent to the weight of the crude drug), warm soak and extract at 90°C for 3 times, each time for 2 hours, filter the extract with gauze, combine the filtrates, and concentrate under reduced pressure to a relative density of about 1.19 . Add ethanol to a final concentration of 80%, let it stand overnight, and remove the supernatant. Add water to dissolve the precipitate to a density of 1.065, then add ethanol to a final concentration of 70%, let stand until no precipitate precipitates, and remove the supernatant. Freeze-dry the precipitate to obtain the total polysaccharide;

[0062] Get the pueraria root and epimedium, add 14 times the amount (equivalent to the weight of the crude drug) ...

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Abstract

A Chinese medicine for treating depression is prepared from pseudostellaria root, pueraria root and epimedium through extracting in water and / or alcohol, separating and post-processing.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine preparation for treating depression and a preparation process thereof, in particular to a Chinese patent medicine prepared according to a specific process by taking heterophylla pseudostellariae, kudzu root and epimedium as raw materials, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Depression is a neurosis characterized by persistent low mood, anxiety, physical discomfort, and sleep disturbance. With the aging of society and increasing social pressure, the incidence of depression increases year by year. An epidemiological study in the United States shows that 15% of people in the community have depressive symptoms (Blazer, D., Burcherr, B ., Service, C., George, L.K. The association of age and depression aming the elderly: an epidemiologic exploration. J. Gerontol, 1991, 46, 210-215). A European study came to the same conclusion (Duf...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K31/715A61P25/24
Inventor 邢东明杜力军王伟张陆军王进玲
Owner 新疆华春生物药业股份有限公司