Biodegradable poly-caprolactone artificial breast wall material and preparation method thereof

Abstract

The invention provides a biodegradable poly-caprolactone artificial breast wall material and preparation method thereof, wherein the material comprises 10-70% of chitosan fiber and balancing ploycaprolactone. When short chitosan fiber is employed, the short chitosan fiber is weighed and mixed with ploycaprolactone and stirred in high speed mixing machine, the premix is compounded, squeezed and granulated with a double bolt extrusion machine, or compounded and squashed with a closed-smelting machine, then is subject to compression moulding on vulcanizing press and cut into samples. The invention also provides the preparing method for the situation when long chitosan fiber is employed.

Description

technical field [0001] The invention relates to an artificial chest wall material and a preparation method thereof, in particular to a biodegradable polycaprolactone artificial chest wall material and a preparation method thereof. used in the biomedical field. Background technique [0002] At present, the materials used in clinical practice to repair chest wall defects can be divided into three categories: autologous tissue, allogeneic tissue, and artificial materials. Autologous tissues include fascia lata, muscle flaps, omentum, iliac bone slices, rib slices, etc. Although they are the most physiological repair materials, they are limited, increase trauma, and most of them are not hard enough. Control, mostly suitable for small defect repair. Most of the allogeneic tissues are preserved ribs after thoracotomy, but they are not widely used due to insufficient sources and inconvenient use. For large chest wall defects, artificial materials are now tended to be used for re...

AI Technical Summary

Problems solved by technology

[0004] The invention aims at the deficiencies and defects of the current artificial repair materials for chest wall defects, and provides a biodegradable polycaprolactone artificial chest wall material and a preparation method thereof, so that the biodegradable artificial chest wall material has sufficient strength and hardness in the bone healing process , can support the fracture site to bear the external force of normal physiological activities; after the bone heals, the material begins to degrade and lose strength, and the external load-bearing force is gradually transferred to the autogenous bone, so that the function of the newly healed autogenous bone can be restored to a normal level. Avoid the hassle and pain of secondary surgery