Drop pills containing bear gall and tendril-leaved fritillary bulb and preparation method thereof
A technology of bear bile and bear bile powder, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve problems such as long dissolution time, low dissolution rate, and inaccurate dosage, so as to avoid gastric Effects of intestinal irritation symptoms, accelerated dissolution and absorption, and improved bioavailability
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[0036] Now with several groups of specific examples, the preparation method of Xiongdan Chuanbei dripping pills of the present invention will be further described.
[0037] Group 1: Tests with a single matrix
[0038] 1. According to the section [Preparation method of a kind of medicinal extract], the extract dry powder containing 4 kinds of pure Chinese medicine active ingredients such as bear bile powder, Chuan Fritillaria, almond water, and menthol was prepared for use;
[0039] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;
[0040]3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0041] 4. Follow the [Preparation Method] to prepare Xiongdan Chuanbei Dropping Pills of various specifications.
[0042] [test results]
[0043...
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