New combination of Cefpirome Sulfate and preparation method

A technology of cefpirome sulfate and its composition, which is applied in the field of new composition of cefpirome sulfate and its preparation, and can solve problems such as being beneficial to the human body

Inactive Publication Date: 2005-08-31
NANJING CHENXIANG MEDICAL RES
View PDF0 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When using a double-chamber bag, there will undoubtedly be a certain amount of carbon dioxide entering the human body. Although it is not certain how harmful the carbon dioxide entering the body is, it is definitely not beneficial to the human body.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Preparation method of aseptic mixed powder of cefpirome sulfate for injection:

[0020] In an environment where the relative humidity of the air is not more than 55%, the cefpirome sulfate and L-arginine aseptic powder are mixed, ground, and passed through a No. 6 sieve to obtain the mixed powder. The prescription composition is shown in Table 3

[0021] Ingredients

Embodiment 2

[0023] Preparation method of aseptic mixed powder of cefpirome sulfate for injection:

[0024] Under aseptic and clean environment and air relative humidity is not more than 55%, cefpirome sulfate and L-lysine aseptic powder are mixed, ground, and passed through No. 6 sieve to obtain mixed powder. The prescription composition is shown in Table 4

[0025] Ingredients

Embodiment 3

[0027] Preparation of Cefpirome Sulfate Sterile Powder Injection for Injection

[0028] Weigh the aseptic mixed powder of cefpirome sulfate for injection obtained by the method in Example 1 (see Table 5 for prescription composition), and fill it in a 10ml vial under an environment of aseptic cleanliness and air relative humidity not greater than 55% , Wipe, full inspection, printing, packaging.

[0029] Ingredients

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A cefpirome sulfate as a newm edicine and its preparing process which features use of alkaline or neutral amino acid as cosolvent are disclosed.

Description

Technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a new composition of cefpirome sulfate and a preparation method thereof. Background technique [0002] Cefpirome sulfate is a fourth-generation cephalosporin antibiotic. Compared with the first, second, and third-generation cephalosporins, the fourth-generation cephalosporin has a broader antibacterial spectrum, is more stable to β-lactamase, and has a higher blood concentration. Can penetrate the blood-brain barrier and so on. It has been clinically proven to have a good effect on superficial secondary infections such as sepsis, trauma, and surgical trauma. Cefpirome has good bactericidal activity against the pathogenic bacteria of bacterial meningitis and has good penetration to the blood-brain barrier, so this product has achieved good curative effect in the treatment of meningitis infection. Although the half-life of cefpirome is relatively short (about 2h), the high con...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/546A61P31/04
Inventor 邢为藩
Owner NANJING CHENXIANG MEDICAL RES
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap