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Compound preparation of piracetam and its use

A piracetam preparation technology, applied in the field of piracetam 0.2-8g pharmaceutical preparations, can solve the problems of inconvenient use for medical personnel and patients, and has not been developed

Inactive Publication Date: 2005-10-12
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Piracetam has been developed into a variety of preparations due to its good physical and chemical properties, including tablets, capsules, granules, oral liquids, injections, intravenous infusions, etc.; inosine, ATP, and vitamin C in the energy mixture formula The three drugs are also often used in combination in clinical practice; clinically, in the treatment of memory loss and mild and moderate brain dysfunction caused by various reasons such as acute and chronic cerebrovascular disease, brain trauma, and various toxic encephalopathy, etc. Most of the energy mixture and piracetam are used in combination, but the compound preparation between piracetam and energy mixture has not been developed so far, which causes great inconvenience to medical personnel and patients in use. In order to facilitate clinical use and To improve the patient's own compliance and ensure the curative effect, we have developed a compound energy preparation for brain surgery on the basis of the compound energy mixture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1: Preparation of regular brain surgery compound energy tablets.

[0042] prescription:

[0043] Inosine 50g

[0044] ATP 5g

[0045] Vitamin C 125g

[0046] Piracetam 200g

[0047] Lactose 100g

[0048] Hypromellose 12g

[0049] Sodium carboxymethyl starch 8g

[0050] Micronized silica gel 2.5g

[0051] Magnesium Stearate 1.5g

[0052] A total of 1000 pieces were made

[0053] Preparation method: pass the drug and auxiliary materials through 80 mesh sieves, weigh inosine, ATP, vitamin C, piracetam, lactose, hypromellose, sodium carboxymethyl starch, micropowder silica gel, magnesium stearate, Mix evenly, and the powder can be directly compressed into tablets.

Embodiment 2

[0054] Example 2: Preparation of brain surgery compound energy capsules.

[0055] prescription:

[0056] Inosine 50g

[0057] ATP 5g

[0058] Vitamin C 125g

[0059] Piracetam 200g

[0060] Microcrystalline Cellulose 80g

[0061] Talc powder 15g

[0062] capsule shell

[0063] A total of 1000 capsules were made

[0064] Preparation method: Sieve the drug and auxiliary materials through 80 sieves, weigh the prescribed amount of inosine, ATP, vitamin C, piracetam, microcrystalline cellulose, and talcum powder, mix evenly, and directly fill the powder into the capsule shell.

Embodiment 3

[0065] Example 3: Preparation of Shennei Er Compound Energy Preparation Oral Liquid.

[0066] Prescription: Inosine 20g

[0067] ATP 2g

[0068] Vitamin C 50g

[0069] Piracetam 80g

[0070] Aspartame 0.5g

[0071] Make a total of 1000ml

[0072] First, weigh the prescribed amount of inosine, ATP, vitamin C, piracetam, and aspartame, and add two-thirds of the total amount of distilled water to the ingredients bucket, stir to dissolve, and use a pore size less than 1.2μm Filter through a microporous membrane, and finally add water to the total amount of the preparation, mix, sterilize, and sub-package into 10ml to obtain the finished product.

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PUM

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Abstract

A high-energy composite medicine for treating acute or chronic cerebrovascular disease, cerebral trauma, toxipathic cerebrosis, hypomneis and cerebral disfunction contains proportionally inosine, ATP, VC and piracetam.

Description

Technical field: [0001] The present invention relates to a kind of compound medicine preparation, especially relates to the medicine preparation containing 0.07g~0.8g inosine, 7~80mgATP, 0.17g~2.0g vitamin C, piracetam 0.2~8g in the preparation of unit dosage . The pharmaceutical preparation of the invention can be widely used in the treatment of memory loss and mild or moderate brain dysfunction caused by various reasons such as acute and chronic cerebrovascular disease, traumatic brain injury and various toxic encephalopathy. Background technique: [0002] Piracetam is white crystalline powder, odorless, bitter in taste, easily soluble in water and slightly soluble in ethanol. It is a GABA analog, which can activate, protect and repair brain cells, increase the ATP / ADP ratio in the brain, promote the absorption of amino acids and phospholipids, protein synthesis and glucose utilization. No sedative, anticholinergic, antihistamine effect, used for senile mental decline sy...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/7076A61P9/10A61P25/00A61P39/02
Inventor 鄂滟严轶东
Owner FUKANGREN BIO PHARMA
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