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Kangai drip pill for treating tumour, hepatitis B and its preparation method

A technology of malignant tumors and polyethylene glycol, which is applied to the medicinal composition of matrine, ginseng, and diseases, which can solve the problems of long dissolution time, heavy economic burden on patients, and low dissolution rate, so as to avoid gastrointestinal irritation Symptoms, enhanced bioavailability, accelerated dissolution and absorption effects

Active Publication Date: 2005-10-26
HUBEI WUSHI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the limitations of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions. At the same time, there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy economic burden for patients, unsuitable for family use and other disadvantages
[0008] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the drug efficacy. The play also directly affects the therapeutic effect
At the same time, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of the Kangai dripping pills of the present invention will be further described.

[0032] [Group 1: Trials with a single substrate]

[0033] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of traditional Chinese medicine astragalus, ginseng and matrine is pre-prepared for use;

[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Kangai Dropping Pills of different specifications.

[0037] [test results]

[0038] Experiment 1: In order to observe the diff...

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PUM

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Abstract

A Chinese medicine in the form of dripping pills for treating the primary cancers of liver, lung, rectum and hymph, gynocological cancer, leukocytopenia, chronic hepatitis B, etc is prepared from astragalus root, ginseng, flavescent sophora root and medicinal carrier. Its prparing process is also disclosed.

Description

technical field [0001] The invention relates to a kind of medicine which has the function of nourishing qi, strengthening the body and enhancing the immunity of the body, and is used for treating primary liver cancer, lung cancer, rectal cancer, malignant lymphoma, gynecological malignant tumor, and leukopenia and leukopenia caused by various reasons, and chronic A pharmaceutical composition for hepatitis B and other diseases, in particular to an oral preparation of a pharmaceutical composition prepared from traditional Chinese medicines astragalus, ginseng and matrine as raw materials. Background technique [0002] Kangai injection prepared according to the formula and extraction process given in the national drug standard WS-11222 (ZD-1222)-2002, is a medicine used for the treatment of primary liver cancer, lung cancer, rectal cancer, malignant Lymphoma, gynecological malignant tumors; leukopenia and decrease caused by various reasons; chronic hepatitis B and other disease...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 曲韵智
Owner HUBEI WUSHI PHARMA
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