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Medicinal composition for treating aphronesia and preparing process thereof

A composition and dementia technology, applied in the field of medicine, can solve the problems of poor patient compliance, frequent administration times, inconvenient use and the like

Inactive Publication Date: 2006-06-14
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the common preparations, the active ingredients therein face a series of problems, such as frequent clinical administration, inconvenient use, poor patient compliance, etc.

Method used

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  • Medicinal composition for treating aphronesia and preparing process thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] The preparation of embodiment 1 common tablet

[0056] Take the following medicinal materials: Astragalus 16.7g, Salvia miltiorrhiza 16.7g, Chuanxiong 10g, Atractylodes atractylodes 10g, Shichangpu 10g, Coptidis 3.3g, borneol 0.0667g;

[0057] Take astragalus and dandelion and add 10 times the amount of water, reflux and extract twice, 1.5 hours each time, filter the extract, and set aside; add 10 times the amount of water to Chuanxiong, Atractylodes atractylodes, and Shichangpu, extract the volatile oil with a volatile oil extractor for 8 hours, and use the volatile oil for later use. Filter out the water extract, add 10 times the amount of water to extract the dregs of the medicine for 1.5 hours, combine the water extract, filter and combine with the Astragalus miltiorrhiza extract and concentrate under reduced pressure to 1ml approximately equal to 1g crude drug, let cool, add 95% ethanol to make the alcohol Concentration is 60%, after standing overnight, filter, rec...

Embodiment 2

[0060] Take the following medicinal materials, astragalus 16.7g, salvia miltiorrhiza 16.7g, chuanxiong 10g, atractylodes 10g, calamus 10g, coptis 3.3g, borneol 0.0667g;

[0061] Add 10 times the amount of water for astragalus and dandelion, reflux extraction twice, 1.5 hours each time, filter the extract, and set aside; add 10 times the amount of water for Chuanxiong, atractylodes, and calamus, extract the volatile oil with a volatile oil extractor for 8 hours, set aside the volatile oil, filter Take out the water extract, add 10 times the amount of water to extract the dregs of the medicine for 1.5 hours, combine the water extract, filter and combine with the extract of Astragalus miltiorrhiza and concentrate under reduced pressure to 1ml approximately equal to 1g of crude drug, let cool, add 95% ethanol to make the alcohol concentration After standing overnight, filter, reclaim ethanol until 1ml is approximately equal to 3g of crude drug, add 95% ethanol, make the alcohol con...

Embodiment 3

[0065] Take the following herbs, astragalus 25.5g, salvia miltiorrhiza 25.5g, chuanxiong 15g, atractylodes 15g, calamus 15g, coptis 7.5g, borneol 0.8g;

[0066] Take astragalus and dandelion and add 14 times the amount of water, reflux and extract twice, each time for 3 hours, filter the extract, and set aside; add 12 times the amount of water to Chuanxiong, atractylodes, and calamus, extract the volatile oil with a volatile oil extractor for 12 hours, and use the volatile oil for later use. Filter out the water extract, add 12 times the amount of water to extract the dregs of the medicine for 3 hours, combine the water extract, filter and combine with the extract of Astragalus miltiorrhiza miltiorrhiza and concentrate under reduced pressure to 1ml, which is approximately equal to 1.5g of crude drug, let it cool, add 98% ethanol, and make Alcohol concentration is 60%, after standing overnight, filter, reclaim ethanol until 1ml is approximately equal to 4g crude drug, add 95% et...

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Abstract

A Chinese medicine in the form of gel skeleton tablet for treating dementia is prepared from astragalus root, red sage root, Chuan-xiong rhizome and hydroxypropyl methylcellulose. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a gel matrix tablet for treating dementia and a preparation method thereof. Background technique [0002] Dementia is a common geriatric disease, and it is also recognized as a refractory disease in the medical field today. According to the report of the World Health Organization, among the elderly over 65 years old, 10% of them have mental disorders, and 60% of them develop dementia, and With increasing age, the incidence of dementia showed a sharp upward trend. Dementia that occurs in old age can be divided into two categories: chronic and acute according to the speed of symptom development: Chronic dementia accounts for about 80% of old age dementia, also known as senile chronic brain syndrome. It includes senile dementia, vascular dementia, and mixed dementia in which the two coexist. In addition, there are some rare dementias, such as sub...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61K9/20A61P25/28
Inventor 郑永锋范立君
Owner TIANJIN TASLY PHARMA CO LTD