Antiradiation injury medicine

A radiation-resistant and drug-resistant technology, applied in drug combinations, pharmaceutical formulations, organic active ingredients, etc., can solve problems such as high toxicity and side effects

Inactive Publication Date: 2006-08-30
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs used to prevent and treat radiation damage in radiation protection and clinical tumor treatment are mostly chemically synthesized drugs, which have relatively high toxicity and side effects. Therefore, it is very necessary to develop natural drugs that can be used together with medicine and food, have strong anti-radiation effects, and have no toxic and side effects. of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] The preparation of the anti-radiation damage medicine of the present invention.

[0072] 1. Extraction of Matsutake polysaccharide: After the dried Matsutake powder is refluxed to remove the fatty substances, the water is extracted three times, and the amount of water added each time is 40 times the volume of the dry powder. The concentration of ethanol is precipitated three times, and after the lysozyme is evaporated to dryness, the solid powder of matsutake polysaccharide is obtained.

[0073] 2. Extraction of ginseng polysaccharides: use a large amount of ginseng root "waste residue" produced in the process of extracting ginsenosides to directly extract with water, the temperature is controlled above 95 °C, and the water is extracted three times, 3h / each time, the filtrate is combined, and the impurities are removed by suction filtration, After heating and concentrating to 1 / 40 of the original solution, it is precipitated three times with ethanol with a concentration...

Embodiment 2

[0077] Preparation of anti-radiation damage drug capsules.

[0078] Weigh 80 g of the active ingredient composition prepared by the method of Example 1 and place it in a mixer, slowly add 15 g of starch while stirring, spray an appropriate amount of pure water, stir at high speed for 5 minutes, pass the wet granules through a 16-mesh sieve, and dry in an oven at 60°C. Whole granules, add 5 g of magnesium stearate, mix well, sterilize, and fill in No. 0 capsules (0.25 g / capsule) to obtain the anti-radiation damage drug in capsule dosage form.

Embodiment 3

[0080] Preparation of anti-radiation damage drug oral liquid.

[0081] Weigh 80 g of the active ingredient composition prepared by the method of Example 1 and place it in a mixer, slowly add 10 g of honey, 6 g of sucrose, 2 g of citric acid, and 2 g of magnesium stearate while stirring, and after mixing, add 1 L of distilled water and mix to prepare. The solution is sterilized and packaged into 100 bottles (10ml / bottle) to obtain the anti-radiation damage drug in the oral liquid dosage form of the present invention.

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PUM

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Abstract

A medicine for preventing and treating the organ injury caused by radiation contains the matsutake polyose (60-80 Wt%) and ginseng polyose (20-40 Wt%) through mixing.

Description

technical field [0001] The invention relates to an anti-radiation damage drug capable of preventing and treating radiation damage. Background technique [0002] In the modern living and working environment, electromagnetic radiation is everywhere. According to the causes of radiation, it can be generally divided into five types: natural radiation mainly refers to sunlight exposure; electrical radiation refers to TV broadcasting equipment, telecommunication products (such as mobile phones, computers, etc.), household appliances (such as induction cooker, microwave oven, etc.) and various industrial equipment electromagnetic radiation; medical radiation refers to X-ray perspective, CT, nuclear magnetic resonance, cobalt 60 High-intensity radiation emitted by radiation therapy, etc.; building material radiation refers to the radiation produced by abnormal radioactive elements in various walls and decorative materials (such as stone, tiles, paint, etc.); the last one refers to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P17/16
Inventor 李娟李雪静李静王宏芳孙志伟徐坤吴新宇侯雷
Owner JILIN UNIV
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