Pharyngolaryngitis-treating pharmaceutical compositions and its preparing method

A composition and technology for pharyngitis, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of many indications and unclear active ingredients, and achieve the effects of stable quality, alleviation of sore throat, and rapid relief of symptoms.

Inactive Publication Date: 2006-10-04
SICHUAN INST OF CHINESE MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This open document reports the crude extract of Iris,

Method used

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  • Pharyngolaryngitis-treating pharmaceutical compositions and its preparing method
  • Pharyngolaryngitis-treating pharmaceutical compositions and its preparing method
  • Pharyngolaryngitis-treating pharmaceutical compositions and its preparing method

Examples

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Example Embodiment

[0029] Example 1 Preparation of total flavonoids of Iris iris, a medicinal extract of the present invention

[0030] (1) The crude drug is crushed into a coarse powder and passed through a 20-mesh sieve, placed in an extraction tank, and extracted with 70% ethanol under heating and refluxing for three times, each time is 1.5 hours, and the amount of solvent each time is 4 times the amount of medicinal materials (v / w) The extracts were combined, filtered, and ethanol was recovered under reduced pressure at 60°C to obtain a syrupy substance (brown-yellow extract) with a specific gravity of 1.2g / ml (measured at 50°C). The yield is 49-51% (w / w) of the feed amount. The above extract is stirred and dissolved with 20 times the amount of boiling water (w / w) equivalent to the amount of raw medicine. When the solution is cooled to 50°C, let it pass through the processed WLD type macroporous adsorption resin tank (resin amount: original The dosage is 3:1, w / w), the flow rate is controlled at...

Example Embodiment

[0033] Example 2 Preparation of pharmaceutical capsules of the present invention

[0034]This product is a hard capsule prepared by directly filling the total iris flavonoids extract. Each tablet containing the total iris flavonoids is calculated as iris glycoside (C2H22O11), not less than 180mg (the average weight of each filled extract of the drug capsule of the present invention is about Is 0.35g).

[0035] Raw material: 350g of iris total flavonoids extract, prepared into 1000 capsules of the present invention

[0036] (1) Crush the dry total flavonoid extract (content> 55%) through a 60-mesh sieve, and fill the No. 1 capsule with a manual or capsule filling machine under the condition of a relative humidity of less than 64%, and control the content to be about 0.35 per capsule g, prepare 1000 grains.

[0037] (2) Dry the iris total flavonoids extract at 60°C (steam oven), and when the water content is less than 4% to be measured, smash through a 60-mesh sieve. Accurately weig...

Example Embodiment

[0038] Example 3 Preparation of pharmaceutical tablets of the present invention

[0039] The dry total flavonoid extract (content>55%) is crushed through a 60-mesh sieve, starch is added, granulated, granulated, and tableted.

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Abstract

The invention discloses a pharmaceutical composition for treating pharyngitis and laryngitis, which contains Iris tectorum Maxim. extract flavones as the active ingredient, and pharmaceutically acceptable adjuvant or supplementary constituents, wherein the content of the extract flavones is greater than 55% calculated by Tectoridin C22H22O11. The effective constituents being Tectoridin, Tectoridin A, Tectorigenin, and wild Tectorigenin, the four ingredients have synergic action.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating pharyngitis, in particular to a pharmaceutical composition in which a traditional Chinese medicine extract is an active part and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] According to traditional Chinese medicine, acute pharyngolaryngitis belongs to the external attack of wind-heat evil poison, and throat obstruction (acute pharyngitis) and acute throat dullness (acute laryngitis) caused by evil heat blocking the lungs are common and frequently-occurring diseases that seriously affect health, often accompanied by Produced by a cold. The onset is acute, with sore throat, hoarseness, headache, fever, and cough with yellow sputum as the main symptoms, and further exacerbation may cause edema and congestion of the throat and nasal mucosa. Modern medicine has confirmed that acute pharyngitis is mostly caused by viruse...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K36/88A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P11/04A61P11/14A61P29/00A61P31/12
Inventor 徐学民袁崇均齐尚斌李利民王笳杨红黄卫平陈帅舒光明
Owner SICHUAN INST OF CHINESE MATERIA MEDICA
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