Dispersed cefditoren pivoxil tablet and its prepn process
A technology for cefditoren pivoxil and dispersible tablets, which can be applied to medical preparations without active ingredients, medical preparations containing active ingredients, pharmaceutical formulas, etc. Good, improve medication compliance, high bioavailability
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[0041] Example:
[0042] According to the calculation of preparing 1000 pieces, the composition and proportion of raw and auxiliary materials are:
[0043] Cefditoren pivoxil 100g
[0044] Microcrystalline Cellulose 50g
[0045] Crospovidone 8g
[0046] Protein sugar 20g
[0047] 3% hypromellose solution
[0048] Magnesium Stearate 1g
[0049] Make 1000 pieces
[0050] Preparation:
[0051] ①The raw and auxiliary materials are passed through a 100-mesh sieve.
[0052] ②Weigh hypromellose, add water to make a 3% solution, and set aside.
[0053] ③Weigh the prescription amount of cefditoren pivoxil, microcrystalline cellulose, protein sugar and half of the prescription amount of crospovidone, mix well, add 3% hypromellose solution to make soft material, 20 mesh granulation , 60 ℃ blast drying, 24 mesh granulation, add the remaining crospovidone and magnesium stearate, and mix.
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