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A pharmaceutical composition capable of improving boar reproductive performance

A reproductive performance and composition technology, applied in the direction of drug combination, active ingredients of hydrocarbon compounds, diseases, etc., can solve the problems of high cost, inconvenient use, increase litter size, etc., and achieve low cost, healthy and long-lasting physiological activities , Increase the effect of litter size

Inactive Publication Date: 2006-12-13
HUAZHONG AGRI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Leptin has functions such as starting puberty, promoting reproductive system development and sexual maturity, maintaining pregnancy, and increasing litter size (see: BjorbaekC et al., Leptin Signaling in the Central Nervous System and the Periphery, Recent Prog, Horm, Res. 2004, 59 (1): 305-331; Madej T et al., Threading analysis suggests that the obesegene product may be a helical cytokine, FEBS Lett, 1995, 373: 13-16), although the application of exogenous Leptin can improve the lean meat percentage of pigs , fecundity has great significance and broad prospects, but at present, no matter whether the method of injecting Leptin or the method of gene fusion is used, there are problems of inconvenient use and high cost, and there is a phenomenon of Leptin resistance in the body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 (preparation embodiment)

[0023] The formula for preparing 10 kilograms of finished pharmaceutical compositions is as follows:

[0024] Glycerin 2000ml

[0025] Olive oil (purchased from Greek product of Greece company; acidity≤1%), 2000ml

[0026] Squalene (purchased from U.S. Healthy Nature Rehource company 3000g;

[0027] Ludukang (purchased from China Shandong Yantai Luye Animal Health Products Co., Ltd.) 500g;

[0028] Wheat flour with water content less than 13% 2500g

[0029] Prepare as follows:

[0030] 1) mixing the glycerin and the olive oil as a diluent;

[0031] 2) Dissolving the squalene into the diluent prepared in step 1) and mixing to obtain the initial product;

[0032] 3) Add chlorotoxin to the initial product of step 2), mix well, then add the wheat flour, mix well, and make it into a granular powder oil;

[0033] 4) The finished medicine described in step 3) is divided into 500 g per bottle, packed in 50 portions, and stored in the...

Embodiment 2

[0037] Embodiment 2 (application embodiment)

[0038] 1. Application test of breeding boars (determination of Leptin content in blood of breeding boars)

[0039] (1) Experimental materials and methods

[0040] Select boars (body weight is 150-200 kg) to take orally 1 part of the pharmaceutical composition of the present invention (10 g of the pharmaceutical composition of the present invention) / day, and use it continuously for 15 days, and carry out blood test results in 60-90 days after drug withdrawal :

[0041] (2) Detect the level of Leptin in the blood of the tested pigs.

[0042] The results showed that 60 to 90 days after the drug was stopped in the experiment, the Leptin (ng / ml) content in the blood of the boars tested continued to significantly decrease, as shown in Table 1:

[0043] Control group (do not contain pharmaceutical composition of the present invention)

Experimental group 1 (containing 3~6g / head / day of the pharmaceutical composition of the...

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Abstract

The invention discloses a medicinal composition for increasing pig's reproductive performance, which is prepared from glycerin, olive oil, spinacene and dried wheat flour.

Description

technical field [0001] The invention belongs to the technical field of animal reproduction, in particular, it is a pharmaceutical composition for improving or improving the reproductive performance of breeding pigs. Vitality, improve the conception rate of breeding sows during artificial insemination, increase the number of litters and healthy litters. Background technique [0002] The improvement in the quality of pig breeds has brought about a decline in reproductive performance. Pig producers have noticed that the application of animal genetics and breeding theory and germplasm determination simultaneous breeding technology has played an important role in improving the yield and quality of lean pigs. At the same time, due to the incompatibility between the multiple characters of the organism, the fertility of the breeding stock is reduced and the resistance to stress is reduced. In tropical and temperate regions, when the temperature is 34°C,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P15/08A23K1/16A61K31/01A23K10/30A23K20/10A23K20/158A23K40/10A23K50/30
Inventor 张维民陈顺友蔡映红
Owner HUAZHONG AGRI UNIV
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