Long chain fatty acyl amide compound and its application
A compound and straight chain technology, applied in the direction of active ingredients of heterocyclic compounds, active ingredients of amides, organic chemistry, etc., can solve the problem of no compound
Inactive Publication Date: 2007-06-06
SHANGHAI SECOND MEDICAL UNIV
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However, prior to the present invention, there have been no published reports of the compounds of the present invention being used for brain protection
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The present invention discloses the long chain fatty amide compound with general expression as shown and its application. The compound of the present invention may be used as nerve protecting agent for treating cerebral ischemia, cerebral apoplexy, Alzheimer disease, Parkinson disease and other nerve system diseases.
Description
Long chain fatty acid amide compound and its application technical field The present invention relates to a long-chain fatty amide compound and its application. The compound can be used as a neuroprotective agent, and thus may be used to treat neurological diseases such as cerebral ischemia, cerebral apoplexy, Alzheimer's disease or Parkinson's disease. Background technique Nerve cells are the main body of the central nervous system, and neuron damage is the main cause of many neurological diseases, such as stroke, Alzheimer's disease (AD), Parkinson's disease (Parkinson's disease, PD) and other neurotrauma, Infection and degeneration are all due to damage to neurons, resulting in partial or complete loss of neurological function. Therefore, the effective protection of neurons is a starting point for the treatment of various neurological diseases. It is generally believed that neuroprotective agents mainly function through the following pathways: preventing calcium influ...
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IPC IPC(8): C07C233/47C07C233/01C07D207/16C07D233/64C07D209/20A61K31/16A61K31/40A61K31/403A61K31/4164A61P25/00A61P25/28A61P25/16
Inventor 姚莉韵陆阳陈红专吴兴军钮因尧张建华
Owner SHANGHAI SECOND MEDICAL UNIV
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