Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof

a technology of biological tissue and intracardiac defect, applied in the field of devices, can solve the problems of devices suffering, particularly worrisome patients, heart failure, etc., and achieve the effect of reducing or minimizing the siz

Inactive Publication Date: 2007-08-23
WL GORE & ASSOC INC
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  • Abstract
  • Description
  • Claims
  • Application Information

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Benefits of technology

[0007] The present invention provides a device for occluding intracardiac defects. The device includes a biological tissue scaffold, as opposed to a synthetic scaffold (e.g., a polyester fabric, ePTFE, Ivalon®, or a metal mesh) as presently used by devices known in the art. In a preferred embodiment, the biological tissue sca

Problems solved by technology

The deformities result from the incomplete formation of the septum, or muscular wall, between the chambers of the heart and can cause significant problems.
Ultimately, the deformities add strain on the heart, which may result in heart failure if they are not corrected.
This i

Method used

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  • Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
  • Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
  • Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof

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Embodiment Construction

[0026] The present invention provides an intracardiac occluder for the repair of intracardiac defects, such as, for example, a patent foramen ovale, an atrial septal defect, a ventricular septal defect, and left atrial appendages. The intracardiac occluder includes a structural framework and a biological tissue scaffold adhered thereto.

[0027]FIG. 1 depicts a cutaway view of a heart 100. The heart 100 includes a septum 104 that divides a right atrium 108 from a left atrium 112. The septum 104 includes a septum primum 116, a septum secundum 120, and an exemplary intracardiac defect 124, which is to be corrected by the intracardiac occluder of the present invention, between the septum primum 116 and the septum secundum 120. Specifically, a patent foramen ovale 124 is shown as an opening through the septum 104. The patent foramen ovale 124 provides an undesirable fluid communication between the right atrium 108 and the left atrium 112. Under certain conditions, a large patent foramen o...

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Abstract

The invention provides an intracardiac occluder, which has biological tissue scaffolds as occlusion shells, for the percutaneous transluminal treatment of an intracardiac defect. The intracardiac occluder includes a proximal support structure supporting the proximal occlusion shell and a distal support structure supporting the distal occlusion shell. In one embodiment, biological tissue derived from the tunica submucosa layer of the porcine small intestine forms the occlusion shells.

Description

CROSS-REFERENCE TO RELATED APPLICATION [0001] This application incorporates by reference, and claims priority to and the benefit of, U.S. provisional application Ser. No. 60 / 385,274, which was filed Jun. 3, 2002.TECHNICAL FIELD [0002] The invention generally relates to devices and related methods for treating intracardiac defects. More particularly, the invention provides an intracardiac occluder with a biological tissue scaffold, and related methods, for the percutaneous closure of intracardiac defects. BACKGROUND [0003] The human heart is divided into four compartments or chambers. The left and right atria are located in the upper portion of the heart and the left and right ventricles are located in the lower portion of the heart. The left and right atria are separated from each other by a muscular wall, the intraatrial septum, while the ventricles are separated by the intraventricular septum. [0004] Either congenitally or by acquisition, abnormal openings, holes, or shunts can oc...

Claims

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Application Information

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IPC IPC(8): A61B17/03A61B17/08A61B17/00A61B17/12
CPCA61B17/0057A61B17/12122A61B17/12172A61F2310/00365A61B2017/00592A61B2017/00606A61B2017/1205A61B2017/00575
Inventor DEVELLIAN, CAROL A.CARR, ROBERT M.
Owner WL GORE & ASSOC INC
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