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Method and Apparatus for Implementing Threshold Based Correction Functions for Biosensors

a biosensor and threshold technology, applied in the field of biosensors, can solve the problems of not being able to achieve the same speed and accuracy, and achieve the effect of reducing the interference of secondary effects

Inactive Publication Date: 2008-11-06
ASCENSIA DIABETES CARE HLDG AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a new and improved biosensor system for detecting substances in a sample. The system uses threshold-based correction functions to account for interference effects and obtain accurate analyte values. The correction functions can be linear or non-linear and may be dependent or independent of the primary measurement. The secondary measurement can include temperature, Hemoglobin, and hematocrit concentration, which are used to minimize interference. The technical effects of the invention include improved accuracy and reliability of biosensor measurements.

Problems solved by technology

While calorimetric tests can be made semi-quantitative by the use of color charts for comparison of the color change of the redox indicator with the color change obtained using test fluids of known glucose concentration, and can be rendered more highly quantitative by reading the result with a spectrophotometric instrument, the results are generally not as accurate nor are they obtained as quickly as those obtained using an electrochemical biosensor.

Method used

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  • Method and Apparatus for Implementing Threshold Based Correction Functions for Biosensors

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Embodiment Construction

[0024]Having reference now to the drawings, in FIG. 1 there is shown a block diagram representation of biosensor system designated as a whole by the reference character 100 and arranged in accordance with principles of the present invention. Biosensor system 100 includes a microprocessor 102 together with an associated memory 104 for storing program and user data and correction curves for implementing threshold based correction of secondary effects in accordance with the present invention. A meter function 106 coupled to a biosensor 108 is operatively controlled by the microprocessor 102 for recording test values, such as blood glucose test values. An ON / OFF input at a line 110 responsive to the user ON / OFF input operation is coupled to the microprocessor 102 for performing the blood test sequence mode of biosensor system 100. A system features input at a line 112 responsive to a user input operation is coupled to the microprocessor 102 for selectively performing the system features...

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Abstract

A biosensor system, method and apparatus are provided for implementing threshold based correction functions for biosensors. A primary measurement of an analyte value is obtained. A secondary measurement of a secondary effect is obtained and is compared with a threshold value. A correction function is identified responsive to the compared values. The correction function is applied to the primary measurement of the analyte value to provide a corrected analyte value. The correction method uses correction curves that are provided to correct for an interference effect. The correction curves can be linear or non-linear. The correction method provides different correction functions above and below the threshold value. The correction functions may be dependent or independent of the primary measurement that is being corrected. The correction functions may be either linear or nonlinear.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to Application Nos. 60 / 557,907, filed Mar. 31, 2004 and 60 / 609,570, filed Sep. 13, 2004, which are incorporated by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention relates generally to biosensors, and more particularly, relates to a method and apparatus for implementing threshold based correction functions for biosensors.DESCRIPTION OF THE RELATED ART[0003]The quantitative determination of analytes in body fluids is of great importance in the diagnoses and maintenance of certain physiological abnormalities. For example lactate, cholesterol and bilirubin should be monitored in certain individuals. In particular, the determination of glucose in body fluids is of great importance to diabetic individuals who must frequently check the level of glucose in their body fluids as a means of regulating the glucose intake in their diets. While the remainder of the disclosure herein will be d...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): C12Q1/00G01N27/416G01N33/487
CPCC12Q1/006G01N27/3274G01N27/416G06F9/00G01N33/487
Inventor MECKLENBURG, GEORGE A.
Owner ASCENSIA DIABETES CARE HLDG AG
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