Insulin-mimetics as therapeutic adjuncts for bone regeneration

a technology of imitation agents and therapeutic adjuncts, applied in the field of imitation agents, can solve the problems of large differences in bone metabolism processes and methods, and cost about $5,000 per application, and achieve the effects of promoting bone healing, reducing costs, and enhancing spinal fusion
US20140322292A1Inactive Publication Date: 2014-10-30RUTGERS THE STATE UNIV
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
RUTGERS THE STATE UNIV
Publication Date
2014-10-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic agents or compositions thereof to patients in need of such treatment are also disclosed.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority under 35 U.S.C. §119(e) to U.S. Provisional Patent Application Ser. No. 61 / 564,822, filed on Nov. 29, 2011, and No. 61 / 718,646, filed on Oct. 25, 2012, and claims priority to International Application No. PCT / US11 / 64240, filed on Dec. 9, 2011, which in turn claims priority under 35 U.S.C. §119(e) to U.S. Provisional Patent Application Ser. No. 61 / 421,921, filed on Dec. 10, 2010, No. 61 / 428,342, filed on Dec. 30, 2010, and No. 61 / 454,061, filed on Mar. 18, 2011, all of which are hereby incorporated by reference in their entireties.FIELD OF THE INVENTION

[0002] The present invention relates to use of insulin-mimetic agents as therapeutic adjuncts for bone regeneration and methods for bone healing or regeneration in patients by local administration of insulin-mimetic agents.BACKGROUND OF THE INVENTION

[0003] About six million bone fractures, including about 600,000 non-union cases, occur annually in the United St...

Claims

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