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Method and computing system for modelling a primate brain

a computing system and primate brain technology, applied in computing models, biological models, instruments, etc., can solve problems such as the inability to directly observe brain dynamics and the limited model

Inactive Publication Date: 2015-07-23
CODEBOX COMPDIENSTE +5
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes a computing system for modelling a human brain using a combination of neuroimaging data and a dynamic model of the brain. The system includes a database with multiple datasets, each containing a dynamic model of the brain and neuroimaging data. The system also includes a simulation component for analyzing and correcting the input data, and a decision engine for fitting the dynamic model to the neuroimaging data. The technical effects of the patent include improved accuracy and efficiency in brain modelling, as well as improved data analysis and interpretation.

Problems solved by technology

One aspect of difficulty in the research of brain function is the inability to directly observe brain dynamics.
Such a model may be limited to only a few selected aspects of brain dynamics that are of interest.

Method used

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  • Method and computing system for modelling a primate brain
  • Method and computing system for modelling a primate brain
  • Method and computing system for modelling a primate brain

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Embodiment Construction

[0011]This application incorporates by reference Ritter et. al., “The Virtual Brain Integrates Computational Modelling and Multimodal Neuroimaging” in Brain Connect. 2013; 3(2): pages 121-45 and Sanz Leon et. al., “The Virtual Brain: a simulator of primate brain network dynamics.” in Front Neuroinform. 2013 Jun. 11; pages 7:10. Furthermore, this application incorporates by reference the source code of the virtual brain app, obtainable from “http: / / www.thevirtualbrain.org / register / ”. The current implementation of the virtual brain app represents a working mode of aspects of the invention implementing some of the features described hereafter.

[0012]The problem is to create a standardized simulation framework for a full primate brain model that allows a) comparison of different modelling strategies / model specifications b) simulating brain activity of individual primates.

[0013]WHY A COMUPTATIONAL MODEL? Brain function—i.e. cognition and behaviour—are generated by complex neuronal interac...

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Abstract

In one aspect the application relates to a computing system for providing data for modelling a human brain comprises a database including a plurality of datasets (or allow access to a plurality of datasets), each dataset including at least a dynamical model of the brain including at least one node and a neurodataset of a neuroimaging modality input. The at least one node include a representation of a local dynamic model and a parameter set of the local dynamic model.

Description

PRIORITY CLAIM[0001]This application claims priority to US provisional application U.S. 61 / 678,950, which is fully incorporated herein by reference.FIELD OF THE INVENTION[0002]This invention relates to a method and apparatus for simulating brain function. In particular, this invention relates to a system that simulates brain function by integrating brain models with measured neuroimaging data.BACKGROUND OF THE INVENTION[0003]Brain function is thought to emerge from the interactions of large numbers of neurons. One aspect of difficulty in the research of brain function is the inability to directly observe brain dynamics. It would be useful to provide an abstract mathematical model of modelled brain dynamics that exhibit a lower complexity than actual brain dynamics. Such a model may be limited to only a few selected aspects of brain dynamics that are of interest. Further model complexity or detail may be added to the model to alter a different range of modelled brain dynamics. Clinic...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G06N3/10G06N3/04
CPCG06N3/04G06N3/10G06N3/049
Inventor MCLNTOSH, ANTHONY RANDALMERSMANN, JOCHENJIRSA, VIKTORRITTER, PETRA
Owner CODEBOX COMPDIENSTE