Blood Plasma Fractions as a Treatment for Aging-Associated Cognitive Disorders

Inactive Publication Date: 2019-10-24
ALKAHEST INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0005]The present invention is based on the production and use of blood products for treating and/or preventing age-related disorders, such as cognitive impairment conditions, age-related dementia, and neurodegenerative disease. The present invention recognizes, among other things, the need for new therapies for the treatment and/or prevention of cognitive impairment, age-related dementia, and neurodegenerative disease. Derived from blood and blood plasma, the present compositions of the invention relate to a so

Problems solved by technology

Aging affects all tissues and functions of the body including the central nervous system, and a decline in functions such as cognition, can severely

Method used

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  • Blood Plasma Fractions as a Treatment for Aging-Associated Cognitive Disorders
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  • Blood Plasma Fractions as a Treatment for Aging-Associated Cognitive Disorders

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Embodiment Construction

1. Introduction

[0044]The present invention relates to the identification and discovery of methods and compositions for the treatment and / or prevention of cognitive impairment, including age-associated dementia and neurodegenerative disease. Described herein are methods and compositions for the treatment of subjects suffering from such disorders, which are aspects of the present invention. The methods and compositions described herein are useful in: preventing cognitive impairment, age-associated dementia, and neurodegenerative disease; ameliorating the symptoms of cognitive impairment, age-associated dementia, and neurodegenerative disease; slowing progression of aging-associated cognitive impairment, age-associated dementia, and neurodegenerative disease; and / or reversing the progression of aging-associated cognitive impairment, age-associated dementia, and neurodegenerative disease. An implementation of the invention includes using blood plasma fractions as treatment, such as one ...

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Abstract

Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]Pursuant to 35 U.S.C. § 119 (e), this application claims priority to the filing date of U.S. Provisional Patent Application No. 62 / 412,258, filed Oct. 24, 2016; the disclosure of which application is herein incorporated by reference.FIELD OF THE INVENTION[0002]This invention pertains to the prevention and treatment of aging-associated disease. The invention relates to the use of blood products, such as blood plasma fractions, to treat and / or prevent conditions associated with aging, such as neurocognitive and neurodegenerative disorders.BACKGROUND[0003]The following is offered as background information only and is not admitted to be prior art to the present invention.[0004]Aging is an important risk factor for multiple human diseases including cognitive impairment, cancer, arthritis, vision loss, osteoporosis, diabetes, cardiovascular disease, and stroke. In addition to normal synapse loss during natural aging, synapse loss is an early pa...

Claims

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Application Information

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IPC IPC(8): A61K38/38A61K35/16
CPCA61K38/385A61K35/16A61K38/38A61P25/28
Inventor BELL, DAVIDGALLAGER, IANBRAITHWAITE, STEVEN P.MINAMI, S. SAKURADANG, VUMCCRACKEN, JOENIKOLICH, KAROLY
Owner ALKAHEST INC
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