The present disclosure provides recombinantly manufactured fusion proteins comprising a GLP-1
protein fragment or an analog thereof linked to a feline
Fc fragment. Embodiments include the administration of the fusion proteins to patients and their use as an
appetite suppressant, for treatment of
obesity, for prevention of
obesity, or for treatment of other conditions associated with
excess weight in cats. Exemplary
Fc fusion proteins and pharmaceutical formulations of exemplary
Fc fusion proteins are provided, in addition to methods of use and preparation.