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6 results about "Oligodendrocyte progenitor" patented technology
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Oligodendrocyte progenitor cells (OPCs), also known as oligodendrocyte precursor cells, NG2-glia or polydendrocytes, are a subtype of glial cells in the central nervous system. They are precursors to oligodendrocytes and may also be able to differentiate into neurons and astrocytes.
Large-scale generation of oligodendrocytes
PCT designated stageWO2026038222A1Nervous disorderNervous system cellsOligodendroglia CellMyelin sheath
A method of generating oligodendroglial progenitor cells and pre-myelinating oligodendrocytes is disclosed. Uses of the cell populations are further described.
Owner:HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD
SOX9 derived oligodendrocyte progenitor cells
Provided is a differentiation agent consisting essentially of SOX9 for generating oligodendrocyte progenitor cells (OPCs) from pluripotent stem cells (PSCs). Also provided are methods of generating PSCs and methods of using PSCs to generate OPCs and oligodendrocytes.SOLUTION: A method comprising culturing pluripotent stem cells (PSCs) to produce a population of cells comprising oligodendrocyte progenitor cells (OPCs), wherein the PSCs express engineered nucleic acids encoding SOX9 at a level sufficient to differentiate the PSCs into OPCs in the absence of other transcription factors encoded by the engineered nucleic acids.SELECTED DRAWING: Figure 2C
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE
Large-scale generation of oligodendrocytes
PCT designated stageWO2026038222A9Nervous disorderNervous system cellsOligodendroglia CellMyelin sheath
A method of generating oligodendroglial progenitor cells and pre-myelinating oligodendrocytes is disclosed. Uses of the cell populations are further described.
Owner:HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD
Methods and compositions for generating oligodendrocyte progenitor cells
PendingUS20260055366A1Nervous system cellsCell culture supports/coatingOligodendroglia CellMultipotential stem cell
Methods for generating pre-oligodendrocyte progenitor cells (pre-OPCs) and oligodendrocyte progenitor cells (OPCs) from human pluripotent stem cells are provided using chemically-defined culture media that allow for generation of pre-OPCs and OPCs in as little as three days. Culture media, isolated cell populations and kits are also provided.
Owner:TRAILHEAD BIOSYSTEMS INC
Methods of making oligodendrocyte progenitor cells
The present disclosure is directed to methods of producing oligodendrocyte progenitor cells (OPCs). In addition, methods of treating demyelinating diseases using oligodendrocyte progenitor cells (OPCs) are also disclosed.
Owner:BLUEROCK THERAPEUTICS LP
SOX9-induced oligodendrocyte progenitor cells
PendingUS20260152719A1Nervous disorderGenetically modified cellsOligodendroglia CellCell Differentiating Agent
Provided herein is a differentiation agent that consists essentially of SOX9 for the production of oligodendrocyte progenitor cells (OPCs) from pluripotent stem cells (PSCs). Also provided herein are methods of producing the PSCs and methods of using the PSCs to produce OPCs and oligodendrocytes.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE