An N-formamidopyrazoline derivative is a compound having General Formula (I) or an
enantiomer, a
diastereomer, an
epimer and a racemate thereof, or a pharmaceutically acceptable salt thereof. The compound is an
antagonist of a ligand-gated non-selective cation channel
receptor subtype P2X3, and can be used for treating or preventing various diseases mediated by the
receptor P2X3.