The utility model discloses a nipple protection cover which comprises an inlet portion, a deformable shoulder portion, a fitting base portion and a cavity, the inlet portion, the shoulder portion and the fitting base portion are made of elastic materials, the shoulder portion integrally extends outwards from the bottom side of the inlet portion, and the cavity is formed in the cavity. The fitting base part integrally extends downwards from the outer side of the shoulder part, the inlet part, the shoulder part and the fitting base part define the cavity, the fitting base part forms an opening of the cavity, the inlet part is provided with a liquid drainage channel, the liquid drainage channel is communicated with the cavity, and the liquid drainage channel is communicated with the cavity. Wherein the shoulder part is deformed when the inlet part is transversely pulled so as to allow the inlet part to transversely swing, and the transverse direction is perpendicular to the extending direction of the inlet part, so that the orientation and the angle of the inlet part are adaptively adjusted to the state of the posture that the mother feeds the infant.