The invention relates to an air flow and multi-stage drum type electrostatic combined foreign fiber separation device, in particular to the air flow and multi-stage drum type electrostatic combined foreign fiber separation device during unginned cotton processing. The separation device comprises a feeding port, an air flow separation device housing, an air flow separation foreign fiber inlet, an air flow opening, a foreign matter negative pressure conveying pipeline, a conveying slide plate, an electrostatic separation device housing, a motor, a roller, a pulley, a belt, an electrode plate, anelectrostatic electrode, an electrostatic separation foreign fiber inlet, a hair brush, a protective cover, a high-voltage electrostatic generator, a grounding terminal and an unginned cotton outlet;compared with the prior art, the device adopts the principle of air flow and multi-stage drum electrostatic combined sorting, and carries out air flow and multi-stage drum electrostatic combination sorting on foreign fibers, the elimination rate of the foreign fibers is higher, and the efficient separation of the unginned cotton and the foreign fibers can be achieved without damage.