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Medicine for treating kidney stone and gall-stone

The invention discloses a medicine for treating kidney stone and gall-stone, according to a calculus formation pathology and a pharmacological experiment formula, the medicine of the invention is prepared by arbutin, desmodium, lichee nucleus, longan nucleus, common fenugreek seed, gecko, pig iron cinder, gynostemma pentaphylla, plantago, Orthosiphon Stamineus, Caulis aristolochiae manshuriensis, bletilla rhizome, magnolia cortex and sweetleaf tea. The materials are natural-green, safe and reliable. A traditional Chinese medicine toxin expelling therapy is used. The medicine is capable of releasing spasm, relieving pain, smoothing skin, sterilizing, softening hardness and dissipating binds, soothing liver and resolving depression, clearing heat and dispersing stagnate, rectifying qi, disinhibiting urine and freeing strangury and benifiting openheartedness, the medicine can directly act on nidus, an organic matter is subjected to releasing, dissolving and biological enzymatic hydrolysis, can comprehensively permeated in a core of the calculus, the calculus can be cracked, melted and dissolved layer by layer from outer part to inner part, and the waste liquid is excreted through human excretion tissue, and the damaged cells can be activated, the gland can be balanced, the organ vitality can be enhanced, the acid-base value of blood can be balanced, the calculus recurrence can be prevented, and the simultaneous treatment of principal and subordinate symptoms effect can be acted.
Owner:王启凌

Polyurethane and preparation method of polyurethane and ROS (Reactive Oxygen Species)-responsive polyurethane drug-loading micelles

ActiveCN109180902AStimulate anti-tumor immune responseDrug and Immunotherapy EnhancementOrganic active ingredientsPhotodynamic therapyDrug synergismCoordination complex
The invention discloses polyurethane and a preparation method of polyurethane and ROS (Reactive Oxygen Species)-responsive polyurethane drug-loading micelles. The method comprises the following steps:dissolving hydrophobic drugs and prepared polyurethane solids into a dimethyl sulfoxide solution, slowly dropwise adding the solution into deionized water while intense stirring, continuously stirring, filling in a dialysis bag of MW=3500 after stirring completion, dialyzing for two days, dialyzing to remove non-entrapped hydrophobic drugs; and finally obtaining the stable ROS-responsive polyurethane drug-loading micelles with near-infrared light photothermal therapy and drug synergism. The preparation method of the polyurethane drug-loading micelles disclosed by the invention is simple and novel, and compared with the novel photosensitizer-ruthenium complex for photothermal therapy and the reported drug carrier before, the carrier disclosed by the invention is stable before subjected tonear-infrared stimulation when bonded into the main polymer chain, and effective release of the drugs and treatment of tumor cells can be realized once the carrier is initiated.
Owner:SICHUAN UNIV
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