Notoginseng floral leaf drop pill in use for cleaning away heat and its prepn. process

The technology of dripping pills and mosaic leaves is applied in the field of Tianqi mosaic leaf dripping pills with heat-clearing effect and the field of preparation thereof, and can solve the problems such as being unfavorable to improve the ability of patients to seek medical treatment, bioavailability of liver and intestine first-pass effect, physical harm to staff, etc. , to achieve the effect of being conducive to labor protection, improving bioavailability and environmental protection

Inactive Publication Date: 2007-11-14
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
The drug content of granules is also low, and it is inconvenient to take
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Tianqihuaye dripping pills of the present invention will be further described.

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of medicinal extract: take g or kg as the unit, and take 20 parts of Sanqi leaf stem, 1 part of Panax notoginseng flower, and the above two flavors, add water and decoct three times, each time for 1 hour, and combine the decoction liquid, filtered, and the filtrate was concentrated below 80°C into a thick paste with a relative density of 1.2 to 1.35, continued to be dried below 80°C, and crushed into dry powder to obtain the final product;

[0031] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0032] 3. Pr...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating palpitation, dizziness, headache, insomnia, etc is prepared from the leaf, stem and flower of notoginseng, etc.

Description

technical field [0001] The present invention relates to a pharmaceutical composition with functions of clearing away heat, cooling blood, calming the liver and suppressing yang, and is used for the treatment of sores and furuncles caused by blood heat, palpitations, irritability, dizziness, headache and insomnia caused by liver heat. , particularly relates to a pharmaceutical composition oral drop pill preparation prepared from two traditional Chinese medicines such as Panax notoginseng leaf stem and Panax notoginseng flower. Background technique [0002] According to the ministerial drug standard WS 3 - Tianqi Huaye granule prepared by the preparation method given in B-3805-98 is a kind of granules with functions of clearing away heat, cooling blood, calming the liver and suppressing yang. It is used for sores and furuncles caused by blood heat. Oral granules for the treatment of palpitations, irritability, dizziness, headache, insomnia and other diseases caused by heat ha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/258A61P25/04A61P25/20A61P17/02A61K127/00A61K133/00A61K135/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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