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Artificial blood vessel

A technology for artificial blood vessels and blood vessels, which can be applied in the direction of blood vessels, devices of human tubular structures, etc., and can solve problems such as thrombosis and cell shedding.

Inactive Publication Date: 2008-10-22
CHONGQING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Although it has a certain effect, it also introduces new problems while solving the original problems: 1) After the polymer degradable material is degraded, the stent material will face the problem of possibly causing thrombus when it is re-exposed to the blood; The attached drugs and cells fall off prematurely due to the inability to withstand the pressure of the physiological environment, resulting in new exposure of the scaffold material to the blood

Method used

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Embodiment Construction

[0010] The following is the design process of the artificial blood vessel:

[0011] 1. Use mechanical aided design software to build a geometric model, use computational fluid dynamics software to simulate and calculate the flow field, and obtain the parameters of the model that can better improve the velocity near the wall:

[0012] The mechanical aided design software solid works is used to construct a series of geometric models, the flow field is simulated and calculated by the computational fluid dynamics software PHOENICS, and the parameters are optimized using the velocity field as an index. The fluid parameters are taken from transparent organic solvent wintergreen oil with a density of 1182kg m -3 , with a viscosity of 0.216g m -1 ·s -1 . Orthogonal design is carried out for the three factors of the pipe length, helical pitch and groove depth of the spiral grooved pipe. There are three levels of pipe length: 120mm, 80mm, and 60mm, three levels of helix pitch: 2mm, 4...

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Abstract

An artificial blood vessel features that the spiral slot with arc cross-section is made on its inner surface for changing the flow field distribution of small-diameter artificial blood vessel to generate the flush of blood to inner surface and increase the shear force of blood, so preventing the deposition of harmful substances on the inner surface.

Description

technical field [0001] The invention relates to an artificial blood vessel structure. Background technique [0002] Vascular grafts have been used for fifty years in bypass surgery and arterial reconstruction. Although large-caliber vascular grafts have achieved great clinical success, the clinical problems of small-caliber (<5-6mm) vascular grafts have not been resolved, because of the limited autologous blood vessels and the failure of synthetic blood vessels due to thrombosis and endothelial hyperplasia, people have been looking forward to Small-bore vascular grafts are a breakthrough and are in great demand in cardiac and peripheral bypass surgery. [0003] In order to solve the patency rate of small-caliber artificial blood vessels, two methods are mainly adopted at home and abroad: 1) Select and optimize the stent material. 2) Surface treatment and modification of the material surface. The starting point for solving the patency rate of the artificial blood vessel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/06
Inventor 王贵学张鹤危当恒唐朝君刘芳邓小燕
Owner CHONGQING UNIV
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