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High flux multiparameter imaging surface plasma resonance test instrument

A technology of surface plasmon and plasma, which is applied in the detection field, can solve the problem of giving multi-parameter quantitative test results and not giving multi-parameter measurement results at the same time, and achieves high-throughput fully automatic detection and modulation range The effect of wide and wide application field

Active Publication Date: 2007-10-03
INST OF ELECTRONICS CHINESE ACAD OF SCI
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Problems solved by technology

[0002] At present, surface plasmon resonance (SPR) testers at home and abroad are usually one channel, and only one parameter is tested at a time. Multi-channel surface plasmon resonance (SPR) testers (currently reported that BiaCore products have at most four channels, according to literature reports There are 9-channel systems), each channel only measures one parameter, and does not give the measurement results of multiple parameters at the same time. Recently, an arrayed surface plasmon resonance (SPR) chip has appeared, but the test results are only qualitative results, and have not yet been given. Multiparameter Quantitative Test Results

Method used

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  • High flux multiparameter imaging surface plasma resonance test instrument
  • High flux multiparameter imaging surface plasma resonance test instrument

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Embodiment Construction

[0021] As shown in Figure 1, it is a schematic diagram of the synchronous scanning structure of the vertical rhombic lever of the present invention. On the basis of the patent authorized by the inventor: ZL. The mechanical scanning structure is adopted based on the modulation principle, but the original horizontal structure is changed to a vertical structure.

[0022] The vertical diamond-shaped lever synchronous scanning structure of the present invention includes a tester base 1, an optical platform 2, a connecting rod group 3, a slider 4, a guide rail 5, a screw 6, a motor 7, a sensor 8, a light source 9, and a CCD image acquisition device 10 and optical prism 11. Plate tester base 1 is arranged vertically, and optical table 2 is fixed horizontally on the upper end of its side, and equilateral triangle optical prism 11 is fixedly arranged on the side of optical table 2, and its corner is vertically downward, on the vertical central axis. The connecting rod group 3 includes...

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Abstract

The present invention is one kind of high flux multiparameter image surface plasma resonance test instrument, and relates to detection technology. The test instrument in synchronous scanning structure has a triangular optical prism, an array surface plasma resonance chip, a micro measuring pond with at least one flow channel, an automatic sampling system communicated with the micro measuring pond, an optical system, a mechanical scanning system, a data acquiring system, an embedded microprocessor, and a computer with information acquiring and processing software and system operating software for controlling the test instrument. It operates in one of three operation modes to complete quantitative high flux multiparameter detection.

Description

technical field [0001] The invention relates to the technical field of detection, and is a novel high-throughput, multi-parameter, and image Surface Plasmon Resonance (SPR) tester. Background technique [0002] At present, surface plasmon resonance (SPR) testers at home and abroad are usually one channel, and only one parameter is tested at a time. Multi-channel surface plasmon resonance (SPR) testers (currently reported that BiaCore products have at most four channels, according to literature reports There are 9-channel systems), each channel only measures one parameter, and does not give the measurement results of multiple parameters at the same time. Recently, an arrayed surface plasmon resonance (SPR) chip has appeared, but the test results are only qualitative results, and have not yet been given. Multiparameter Quantitative Test Results. Contents of the invention [0003] The invention proposes a novel high-throughput multi-parameter image surface plasmon resonance ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/55
Inventor 崔大付蔡浩原王军波李亚亭梁金庆刘长春王于杰郑自攀
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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