Meclofenoxate hydrochloride medicine use

A technology of meclofenoxate hydrochloride and new uses, applied in the field of medicine

Active Publication Date: 2007-11-14
珠海晨安医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report that meclofenoxate hydrochloride has a medical effect on femoral head necrosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] The present invention further illustrates the effect of the present invention through the following experimental data.

[0008] 1. Experimental materials:

[0009] 1.1 Animals

[0010] Experimental animals: Adult Japanese white rabbits, 2.1-3.0kg, provided by the Experimental Animal Center of Hunan Drug Inspection Institute, certificate number SYXK (Xiang) 2003-0006.

[0011] 1.2 Medicines and reagents

[0012] Meclofenoxate Hydrochloride for Injection: (Sino-US joint venture) Shanxi Pude Pharmaceutical Co., Ltd., specification: 0.25g / bottle; batch number: 030901; dilute with water for injection before use.

[0013] Prednisolone acetate: produced by Hubei Pharmaceutical Factory, specification: 125mg / 5ml, batch number: 20040918.

[0014] Penicillin Sodium for Injection Southwest Pharmaceutical Co., Ltd., specification: 800,000 U, batch number: 20040309, dilute with water for injection before use.

[0015] 2. Experimental methods and data

[0016] 2.1 Animal grouping

[0017]...

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PUM

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Abstract

The present invention relates to a new application of meclofenoxate hydrochloride for preparing medicine for curing necrosis of femoral head with good therapeutic effect. The invented medicine can be made into injection preparation, also can be made into oral preparation, for example meclofenoxate hydrochloride capsule, etc. Said invention also provides its application method.

Description

Technical field [0001] The invention relates to a new medical use of meclofenoxate hydrochloride, that is, the application of meclofenoxate hydrochloride in the preparation of a medicine for treating femoral head necrosis, and belongs to the technical field of medicine. Background technique [0002] Femoral head necrosis is a pathological process that mainly changes the death of the living components of bone (bone cells, bone marrow hematopoietic cells and fat cells). Femoral head necrosis is a stubborn disease in the world. Due to its complicated etiology, difficult treatment, and high disability rate without timely treatment, it seriously endangers the life and work of patients, so it is called "undead cancer", which shows how harmful it is. Osteonecrosis is the most common with femoral head necrosis. According to reports, the number of new cases of femoral head necrosis in my country is between 150,000 and 200,000 each year, and the cumulative number of cases requiring treatme...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/221A61P19/08
Inventor 刘遵路李润宝余辉陈雪红杨旸
Owner 珠海晨安医药有限公司
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