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Plants active component composition for curing sick headache as well as its preparing method and application

A technology of active ingredients and compositions, applied in the field of plant active ingredient compositions, can solve the problems of high liver and kidney toxicity, and achieve the effects of anti-platelet aggregation, preventing thrombosis, and lowering blood pressure

Inactive Publication Date: 2008-04-09
北京联合伟华药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because migraine is a long-term and recurrent disease, taking it for a long time will have a great toxic effect on the liver and kidney.

Method used

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  • Plants active component composition for curing sick headache as well as its preparing method and application
  • Plants active component composition for curing sick headache as well as its preparing method and application
  • Plants active component composition for curing sick headache as well as its preparing method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh 500g of Gastrodia elata, pulverize, add 10 times the amount of 70% ethanol, soak overnight, reflux and extract 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure at 60°C to an infusion solution with a relative density of 1.25. paste, add ethanol to make the alcohol content 60%, let it stand for 24 hours, centrifuge, take the supernatant, concentrate under reduced pressure at 60°C to the extract with a relative density of 1.30, add 50g of feverfew extract, mix well, and vacuum dry , and pulverize to obtain the active composition. Add pharmaceutically acceptable auxiliary materials to the active component, and prepare preparations (1000 preparation units) according to conventional pharmaceutical methods.

Embodiment 2

[0039] Weigh 500 g of Uncaria uncaria, pulverize, add 10 times the amount of 70% ethanol, soak overnight, reflux extraction 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure at 60 ° C to a relative density of 1.25 For the extract, add ethanol to make the alcohol content 60%, let it stand for 24 hours, centrifuge, take the supernatant, concentrate under reduced pressure at 60°C to the extract with a relative density of 1.30, add 50g of feverfew extract, mix well, and vacuum Drying and pulverizing to obtain the active composition. Add pharmaceutically acceptable auxiliary materials to the active component, and prepare preparations (1000 preparation units) according to conventional pharmaceutical methods.

Embodiment 3

[0041] Weigh 1000 g of Uncaria uncaria, crush it, add 10 times the amount of 70% ethanol, soak it overnight, reflux extraction 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure at 60 ° C to a relative density of 1.25 For the extract, add ethanol to make the alcohol content 60%, let it stand for 24 hours, filter, take the filtrate, concentrate under reduced pressure at 60°C to the extract with a relative density of 1.30, add 10g of Feverfew Chrysanthemum extract, mix well, and vacuum dry. The active composition is thus obtained. Add pharmaceutically acceptable auxiliary materials to the active component, and prepare preparations (1000 preparation units) according to conventional pharmaceutical methods.

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PUM

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Abstract

The invention designs a plant active ingredient composition for curing the migraine headache, and consists of a feverfew extract and at least a plant chosen from a gastrodia tuber or gambirplant, and the components are formed according to a certain proportioning by weight. Through extracting the active ingredients in the gastrodia tuber or gambirplant, the active ingredients in the gastrodia tuber or gambirplant and the feverfew extract are formed into the active ingredient of the invention, auxiliary materials accepted on the medicine production are added into the active ingredient to be made into a routine preparation type. The active ingredient composition of the invention can be used to cure the vascular migraine headache and the neural migraine headache, and has the obvious function on the aspects of preventing the blood platelets from aggregating and the thrombus from forming, and decreasing the blood pressure.

Description

technical field [0001] The present invention designs a plant active ingredient composition for treating migraine, especially a composition with plant extracts as the active ingredient. The present invention also designs the preparation method and application of the composition in the field of pharmacy, which belongs to traditional Chinese medicine field. Background technique [0002] Migraine, also known as angioneurotic headache, is a common clinical disease characterized by diffuse or unilateral attacks, severe pain, and recurrent attacks. According to foreign data, the incidence rate of migraine is 12.9-17.6% for women and 3.4-6.1% for men. Epidemiological surveys show that the prevalence of migraine in my country is 985.2 / 100,000, and the annual incidence rate is 79.7 / 100,000. Due to the recurrent attack of this disease, which is protracted and difficult to heal, causing great pain to patients, it has always been regarded as a difficult disease by doctors. The research...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/06
Inventor 张树祥熊国裕
Owner 北京联合伟华药业有限公司
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