Novel electric-controlled multi-use spinal cord beating device

Abstract

A multipurpose spinal cord hit device, which is used for the manufacture of an animal model of spinal cord injured, includes a spinal cord hit system1, an electrical control system 2 and a fixed device of the spinous process of the animal spine 3. The spinal cord hit system is provided with an adjustable elastic protection device, an electronic height scale 18 which can be reset to zero, a liquid crystal suggesting screen 19, an impact bar and a guide sleeve with changeable equipment of different diameter and weight. The electrical control system comprises an electromagnetic control circuit and a suggesting circuit of impact and contact, wherein, the electromagnetic adsorption terminal disc made of the electromagnet is arranged on the upright top position of the guide sleeve. The hit device can be used for test animals of various species, owing to the reliable fixed device of the spinous process of animal spine with different size. The hit of the electrical control hit bar is accurate, constant and effective. The electronic scale can control hit height accurately. The suggesting circuit of impact and contact can be used for manufacturing the animal model of spinal cord injured of different injured level and standardization. The anti-error hit device can avoid accidental hit.

Description

Technical field [0001] The invention relates to a novel electronically controlled device for striking the spinal cord of animals for making spinal cord injury animal models, in particular to a novel electronically controlled multipurpose spinal cord striker which can be universally used for rodents, primates and other large and small experimental animals. Background technique [0002] Spinal card injury (SCI), SCI is a disease with a high disability rate. So far, no breakthrough has been made in the treatment of spinal cord injury. A highly reliable and reproducible spinal cord injury model is crucial for elucidating the pathophysiological mechanism of spinal cord injury and evaluating the effects of post-injury interventions. Since Allen first used the Weight-Dropping and WD method in 1911, many scholars have studied and improved the animal model of spinal cord contusion, but most of these improved devices are very expensive and have a low degree of marketization. Research...

AI Technical Summary

Problems solved by technology

This device has its disadvantages: 1. There is no animal spine spinous process fixation device, which is easy to cause inaccurate strikes; 2. There is no anti-mistaken strike device, which is prone to accidental strikes; 3. There is no strike prompt device, which can cause small damage when required It is impossible to determine whether the spinal cord is hit or not; 4. The manual control releases the impact rod, and the accuracy is poor; 5. The manual determination of the impact height is inaccurate

Therefore, the strike effect of this scheme is not stable enough and effective, and its scope of application is narrow, so it cannot be used universally for rodents and primates.

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