Quality control method of 'sifangweipian'

Abstract

The invention relates to a quality control method of a four-ingredient stomach tablet, which increases the following steps in the original quality control method: (1) the invention adopts the microscopic identification method for the identification of thunberg fritillary bulb, cuttlebone, Szechwan Chinaberry fruit and bitter apricot seed which are contained in the four-ingredient stomach tablet; (2) the invention adopts the thin layer chromatography and uses the yanhusuo control medicine and the tetrahydropalmatine positive control for the identification of yanhusuo which is contained in the four-ingredient stomach tablet; (3) the invention adopts the high performance liquid chromatography for the measurement of the content of berberine hydrochloride; the quality control method of the four-ingredient stomach tablet of the invention can not only increase the content measurement method of the active ingredients and the qualitative identification method, but also improve the specificity and quality stability of the quality control method of the four-ingredient stomach tablet, so the invention can ensure the safety and effectiveness of the medicine. The quality control method of the four-ingredient stomach tablet of the invention can not only be used for the control of the quality of the four-ingredient stomach tablet, but also control the quality of other formulations, such as capsules, granules and so on with the same prescription.

Description

Technical field [0001] The present invention involves the qualitative and quantitative detection method of proprietary Chinese medicines. Specifically, the invention involves the qualitative and quantitative detection method of Chinese pads. Background technique [0002] Sifang gastric tablets are a patent -making Chinese patent medicine. It has been listed in my country for many years. It is clinically used in stomach pain, excessive gastric acid, indigestion, stomach and duodenal ulcer.Sifang gastric tablets are prepared by traditional Chinese herbal medicine Haiyu, Zhejiang Fritillaria, Agarwood, Coptis chinensis, Sichuan Skinzi, Shishuang, Bite Almond, Yanhu Mo, and Evodia.The quality standards of this product are collected in the "Pharmaceutical Standards for the Ministry of Health of the People's Republic of China", the 14th volume of the Chinese medicine prescription preparation, the standard number WS 3 -B-0911-91.In this standard, there are only the qualitative identifi...

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to overcome the qualitative identification method of only two kinds of medicinal materials in the current quality standard of Sifangwei Tablets, the specificity is not strong, and it is not conducive to controlling product quality. Disadvantages, provide a qualitative and quantitative detection method for Sifangwei Tablets with strong specificity and more accurate control of product quality