Medicament for treating common cold cough, method for preparing its preparation and quality control method thereof

A traditional Chinese medicine preparation and preparation technology are applied in the field of preparation of medicines and preparations, and can solve the problems of western medicines with large side effects, rapid onset of colds, and easy generation of drug resistance.

Active Publication Date: 2010-05-12
SHANDONG MINGREN FURUIDA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the rapid onset of colds and complex and diverse symptoms, so far there is no single drug that can solve all these problems
Western medicine usually uses antipyretic analgesics, antibiotics, nasal mucosal vasoconstrictors, histamine antagonists, antiviral drugs, etc. to relieve symptoms, but western medicine generally has the characteristics of large side effects, and it is easy to produce drug resistance. At the same time, to a certain extent, the immunity of the human body is also reduced, and the purpose of curing cannot be fundamentally achieved.

Method used

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  • Medicament for treating common cold cough, method for preparing its preparation and quality control method thereof
  • Medicament for treating common cold cough, method for preparing its preparation and quality control method thereof
  • Medicament for treating common cold cough, method for preparing its preparation and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Add the six flavors of the original cold and cough granule prescription, except eucalyptus oil, and the other five flavors such as honeysuckle, and decoct twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.12-1.14 ( 60°C), add 3 times the amount of ethanol, refrigerate (-2~2°C) for 24 hours, filter, recover ethanol from the filtrate, concentrate under reduced pressure to a thick paste (d=1.25~1.30, 60°C), add starch Appropriate amount, mixed evenly, granulated, and dried; eucalyptus oil was subjected to β-CD inclusion to obtain inclusions, and mixed with the granules to obtain the extracted dry granules of the present invention.

Embodiment 2

[0014] Add the six flavors of the original cold and cough granule prescription, except eucalyptus oil, and the other five flavors such as honeysuckle, and decoct twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.12-1.14 ( 60℃), add 3 times the amount of ethanol, refrigerate (-2~2℃) for 24 hours, filter, recover ethanol from the filtrate, concentrate under reduced pressure to a thick paste (d=1.25~1.30, 60℃), add paste Appropriate amount, mixed evenly, granulated, and dried; eucalyptus oil was subjected to β-CD inclusion to obtain inclusions, and mixed with the granules to obtain the extracted dry granules of the present invention.

Embodiment 3

[0016] Add the six flavors of the original cold and cough granule prescription, except eucalyptus oil, and the other five flavors such as honeysuckle, and decoct twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.12-1.14 ( 60°C), add 3 times the amount of ethanol, refrigerate (-2~2°C) for 24 hours, filter, recover ethanol from the filtrate, concentrate under reduced pressure to a thick paste (d=1.25~1.30, 60°C), add lactose Appropriate amount, mixed evenly, granulated, and dried; eucalyptus oil was subjected to β-CD inclusion to obtain inclusions, and mixed with the granules to obtain the extracted dry granules of the present invention.

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PUM

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Abstract

The invention relates to a medicament for curing cold and cough, and is characterized by providing a process for preparing a traditional Chinese medicine preparation namely tablets treating cold and cough by reforming granule form medicaments for curing cold and cough. The technical proposal of the invention is that an extraction technology is optimized and screened, and the modernized novel equipment, novel technology and novel method are adopted by the invention, which are suitable for larger industrial production. The study on quality standard is improved and completed on the basis of original standard, thin layer identification and determination methods are newly determined, all the medicaments are in quality control, the standard of the product quality is advanced and controllable, and the clinical curative effects are guaranteed.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a medicine for treating cold and cough and a preparation method thereof. Background technique [0002] Cold, commonly known as "cold", also known as upper respiratory tract infection, is a common respiratory disease caused by a variety of viruses. It is the most common multiple disease in the world, including common cold and influenza. Symptoms include dry itching or burning sensation in the throat, sneezing, nasal congestion, and runny nose, which may be accompanied by sore throat; generally there is no fever and systemic symptoms, or only low-grade fever and headache. Almost everyone has a cold at some point in their life. Show according to relevant statistical data, about 85% people will catch 3 colds a year on average. Flu not only affects people's life and work, for the elderly, infants, pregnant women and some people with other diseases, flu is a ver...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K9/28A61K36/904A61K36/73A61K36/61A61K36/428A61K36/35A61K36/34A61P11/14G01N30/90
Inventor 张玲尚立霞王妮贾美春邵成雷杨海霞孙英法王欢王国强殷成强
Owner SHANDONG MINGREN FURUIDA PHARMA
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