37results about How to "Wide range of therapeutic effects" patented technology

There is disclosed a method for preventing CCL4 (carbon tetracloride) induced liver damage comprising the prophylactic administration of extracts of Morinda citrifolia. The Morinda citrifolia may be administered in solid or liquid forms. Several regimens are disclosed including the administration of 2 ounces twice daily in a liquid form such as that sold by Morinda, Inc.

The present invention features a method of inducing an anti-angiogenesis effect within a tumorous region in the body of a mammal, wherein the method comprises the steps of administering, to a patient, a formulation comprising processed Morinda Citrifolia, wherein the processed Morinda citrifolia blocks formation of new blood vessels within a tumorous region by inhibiting tubule elongation and endothelial cell migration. Blocking the growth factors of said endothelial cells within said tumorous region inhibits tubule elongation and endothelial cell migration. In a preferred embodiment, the processed Morinda citrifolia comprises fruit juice and puree juice in various concentrations.

The invention discloses semen hoveniae health drink with functions of dispelling effects of alcohol and protecting liver, and a preparation method of the semen hoveniae health drink, and in particular relates to the field of health drink. Every 1000g of the finished product drink is prepared from 0.4-0.6g of taurine, 0.06-0.12g of inositol, 0.0003-0.0018g of nicotinic acid, 0.0004-0.0016g of vitamin B6, 0.00006-0.00018g of vitamin B12, 0.25-0.5g of vitamin C, 75-106g of a sweetening agent, 4.5-7g of a sour agent and 880-920g of water. The drink provided by the invention contains a semen hoveniae extract, a kudzuvine root extract and corn oligopeptide powder which have the functions of dispelling effects of alcohol and protecting liver and is rich in the nutritional ingredients such as the taurine, the vitamin B6, the vitamin B12 and the vitamin C which can replenish physical strength and relieve asthenopia; the raw materials supplement each other and are scientific in proportion; the health drink is high in raw material quality and definite in curative effect, and can effectively and rapidly decompose alcohol toxin, protect liver and regulate the stomach and intestines, thus being an excellent liquor mate; the health drink can be both drunk before or after drinking and drunk while drinking; the health drink enables people not to be drunk during drinking and enables the people to maintain healthy spirit and physique.

A method and composition for reducing the symptoms of the common cold and flu in a human subject in need thereof, comprising the administration of an effective amount of an aqueous composition having all components dispersed as a dry powder concentrate or dissolved in a decoction therein comprising Black pepper, Cinnamon, Cumin, Ginger, Rose hip, Saffron, and Turmeric with Maple Syrup as a sweetener.

The invention relates to a kit and particularly relates to a kit for editing or repairing human hemoglobin gene. The kit comprises sgRNA of specific target HBB gene or a carrier containing the nucleotide sequence of the sgRNA; and / or modified Cas9 enzyme or a sequence encoding the modified Cas9 enzyme or a carrier containing the sequence encoding the modified Cas9 enzyme; and / or a donor gene sequence for repairing the HBB gene of beta-thalassemia or a carrier containing the donor gene sequence. The invention also provides an application of the kit in cutting or repairing the HBB gene, especially an application in repairing the HBB gene of autologous hematopoietic stem cells of a patient with beta-thalassemia. The kit provided by the invention has the advantages that the targeting capability of the target HBB gene is strong, the cutting efficiency of the HBB gene is high, the off-target efficiency is low, the HBB gene can be effectively repaired and the prospect in clinical study and treatment application is wide.

The invention discloses selenium-rich refined tea with multiple efficacies, which is an instant tea series of products produced by using tea polyphenol, nano selenium, witloof inuline and stachyose as raw materials. Other auxiliary materials can be added or not according to special requirements on product properties. Compared with traditional tea leaf and tea polyphenol beverage with single component, the product has the characteristics of reasonable formula and wide application, can be used for daily health care and adjuvant therapy of certain diseases, and has active promotion value.

This invention relates to a biological functional fluorescent magnetic nanometer particle and preparation method and application. The particle has core-shell structure, including: fluorescent material and magnetic material of kernel layer; the shell layer formed by fluorescent transparent material; and the modified layer above the shell layer surface with organic functional group. Through reverse microemulsion, it cans synthesis nanometer particles with both fluorescent and magnetic function, and process chemical modification on its surface to make biological functional magnetic nanometer particles. The nanometer particles can be used for biological marking, biological imaging and biological separation, etc.

The invention relates to a drug combination for preventing and treating cardiovascular diseases, in particular to drug using EPA and vitexin as main active ingredients. The drug combination is formed by combining polyunsaturated fatty acid with c-glycosyl flavone. Experimental studies show that the combination has obvious improving and treating effect on cardiovascular system diseases. Raw materials used for the drug combination are extensive in source, natural, nontoxic, little in side effect and low in cost, and the drug combination has high actual application value.

The invention relates to a copper abietate raw drug and a preparation method thereof; the copper abietate raw drug comprises the following components in parts by weight: 10-80 parts of rosin, 1-40 parts of inorganic copper, 1-40 parts of an organic acid, 2-50 parts of an organic solvent, and 0.01-0.5 part of a catalyst. The preparation method comprises the steps: mixing evenly 10-80 parts by weight of the rosin, 2-50 parts by weight of the organic solvent and 1-40 parts by weight of the organic acid, adding into a sealed reaction kettle with a vacuum reflux unit, heating and stirring, after the rosin is completely dissolved, adding 1-40 parts by weight of inorganic copper, then adding 0.01-0.5 part by weight of the catalyst, heating up and carrying out a refluxing reaction, recycling a reflux condensed fluid, discharging, and cooling to obtain the copper abietate raw drug. The copper abietate raw drug obtained by adopting the copper abietate raw drug synthesis formula and the preparation method has the advantages of being high in content, suitable for preparation of a variety of forms of copper abietate bactericide products and the like.

The invention relates to the field of biological medicine, and discloses a fully human monoclonal antibody for resisting novel coronavirus and application of the fully human monoclonal antibody. An SARS-CoV2 receptor binding domain (RBD) is used as a probe, flow cytometry is used for screening B lymphocytes of a new coronary pneumonia rehabilitation patient, and the affinity constant of the prepared monoclonal antibody and the RBD is 4.03 nM. X-ray crystal diffraction is used for analyzing the three-dimensional structure of the antibody and RBD compound to find that binding epitopes of the antibody and a host cell receptor (ACE2) are overlapped, binding of the RBD and the ACE2 can be competitively blocked, the virus is prevented from infecting host cells, some genetic mutations of the new coronavirus can be coped with. The median effective concentration (IC50) for blocking pseudoviruses (accumulated B.1. 1.7 mutant strain genes and D614G) from infecting host cells is 0.12 ng / mL, and the application prospect of diagnosing, treating and preventing the new coronal pneumonia is achieved.

The invention relates to application of ectoine and derivatives thereof in preparing medicament for preventing and treating digestive tract diseases caused by chemotherapy medicaments. The inventor is surprised to find in researches that: the ectoine and derivatives thereof have unexpected treatment effect digestive tract diseases caused by chemotherapy medicaments, contribute to relieve pains ofpatients who receive chemotherapy, and improve the tolerance dose of the patients to the chemotherapy medicaments. Therefore, the medicament prepared by the ectoine and derivatives thereof can be applied to prevention and treatment on digestive tract inflammation caused by the chemotherapy medicaments. The invention also provides a medicament for treating digestive tract diseases caused by the chemotherapy medicaments, consisting of the ectoine or derivatives thereof and medically acceptable pharmaceutic adjuvant. Compared with the conventional Mesna and other medicaments, the ectoine and derivatives thereof have wide treatment effect on the digestive tract inflammation caused by the chemotherapy medicaments.

The invention discloses a Chinese patent medicine for treating cervical spondylosis and cerebral neurovascular diseases and a preparation method thereof, which uses turtle shells, Polygonum multiflorum, Gastrodia elata, angelica, silkworm, scorpion, salvia miltiorrhiza, Panax notoginseng, safflower, peach kernel and chuanxiong , earthworm, frankincense, myrrh, and asarum are used as raw materials. After processing, they are formulated in a certain proportion. They have the effects of nourishing the kidney and brain, softening the liver and quenching wind, dredging collaterals and relieving pain. They are used to treat common neck and shoulder pain caused by cervical spondylosis. , headache, dizziness, blurred vision, numbness and pain in the limbs, tinnitus, nausea, dark purple tongue or petechiae, ecchymosis, poor blood supply to the brain arteries, and a series of symptoms such as neurological dysfunction.

The invention discloses a fragrant and appetizing traditional Chinese medicine sachet. The sachet comprises the following components: by weight, 8-15 parts of cortex cinnamomi, 8-15 parts of common fennel, 8-15 parts of syzygium aromaticum, 3-5 parts of fructus amomi, 8-15 parts of rhizoma galangae, 8-15 parts of rhizoma acori graminei, 8-15 parts of pericarpium citri reticulatae, 8-15 parts of radix aucklandiae, 3-5 parts of nutmeg, 8-15 parts of amomum tsaoko, 8-15 parts of perilla leaf, and 8-15 parts of herba eupatorii. The fragrant and appetizing traditional Chinese medicine sachet has medicine smell, and the smell can be inhaled by the mouth and nose. The meridian vessel is unblocked, and the effects of eliminating pathogens to reinforce healthy qi and preventing illness and building fitness are reached. The treatment effect of traditional Chinese medicine is wide, and the sachet has effect of protecting stomach, especially can improve the symptoms of stomachache, belching and the like. The effect is obvious and safe after using the traditional Chinese medicine to regulate qi and harmonize stomach. The sachet uses a plurality of fragrant medicinal materials, and the medicaments in the sachet send out continuous fragrance. The fragrance can be inhaled respiratory tract and stimulates the respiratory mucosa of human, and the medicaments are absorbed to effect.

The invention discloses a Chinese patent medicine for treating pain, numbness and dysfunction of the waist and legs and a preparation method thereof. A, Frankincense, Panax notoginseng, Xu Changqing, Zelan, Salvia miltiorrhiza, and Achyranthes bidentata are used as raw materials. After processing, they are prepared in a certain proportion. , for the treatment of hyperosteogeny, lumbar spondylosis, sacral spondylosis, lumbago and leg pain, numbness, paralysis, paralysis and dysfunction of lower limbs.

The invention discloses a production method of a shiitake polysaccharide beverage. The production method includes: sequentially inoculating a shiitake strain into rejuvenation culture media differentin types for culture rejuvenation, wherein culture time in the rejuvenation culture medium of each type is 18-22d; inoculating a strain with good growth vigor into a liquid culture medium for multistage amplification culture, and performing shaking culture at each stage at 23-27 DEG C for 5-7d, wherein inoculating amount of each stage is 10-30%; holding temperature of thallus culture liquid obtained by multistage amplification culture at 63-67 DEG C for 1.5-2.5h to break cells, using a filter net with 80-120 meshes for coarse filtering, and using a filter net of 270-325 meshes for fine filtering to obtain the shiitake polysaccharide beverage. By adopting liquid culture, the problem in the prior art is solved, side effect of shiitake polysaccharide capsules is avoided, and effective actionof various ingredients of shiitake are given into maximum play.

The invention relates to a preparation method and application of a refined ginseng-pilose antler component with anti-Alzheimer's disease activity, and belongs to the field of traditional Chinese medicine development. The method mainly comprises the following steps: extracting ginseng and pilose antler coarse powder containing an ethanol aqueous solution, collecting filtrate, and carrying out membrane separation on the filtrate to obtain the ginseng-pilose antler drug refined component against Alzheimer's disease. The refined component capable of resisting the Alzheimer's disease is separated from the ginseng and pilose antler medicine pair for the first time, the preparation method is clear, the Alzheimer's disease resisting effect is obvious, the reliability of the effect of traditional Chinese medicine is guaranteed, and a foundation is laid for extraction and separation of effective components of the traditional Chinese medicine. The ginseng and pilose antler are expected to be developed into food or health care products which take ginseng and pilose antler as raw materials and have wide treatment effect and commercial development value, and the method has a positive effect on promoting the development of medicines with local characteristics in northeast China.

The invention relates to a medicinal composition for preventing or treating cystitis caused by chemotherapy. The medicinal composition consists of mesna, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carbonic acid or a 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carbonic acid derivative and a pharmaceutically acceptable medicinal carrier. The combined medication of the 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carbonic acid as well as the derivative thereof and the mesna has an unexpected therapeutic effect on preventing or treating the cystitis caused by a chemotherapeutic medicament. The medicinal composition contributes to relieving the pain of a chemotherapy patient; and the tolerance dose of the patient to the chemotherapeutic medicament is improved. Compared with the conventional medicamentssuch as the mesna and the like, the medicinal composition has the advantages that: the composition of the 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carbonic acid as well as the derivative thereof and the mesna has a wide therapeutic effect on the cystitis caused by the chemotherapeutic medicament and has a limited prevention effect.

An encapsulated vagina cleaning liquid is disclosed. The encapsulated vagina cleaning liquid comprises 3-5 parts by weight of alkannin prepared through CO2 supercritical extraction, 1-2 parts by weight of fibralactone prepared through CO2 supercritical extraction, 4-5 parts by weight of propolis prepared through CO2 supercritical extraction, 83-88 parts by weight of purple perilla seed oil prepared through CO2 supercritical extraction, 1-2 parts by weight of egg yolk lecithin and 2-4 parts by weight of Chinese angelica ligustilide, with the encapsulated vagina cleaning liquid being 100 parts by weight. A preparing process includes heating the purple perilla seed oil prepared through CO2 supercritical extraction to 55-65 DEG C, adding 1 part of the weighed fibralactone, 4 parts of the alkannin, 5 parts of the propolis, 2 parts of the egg yolk lecithin and 3 parts of the Chinese angelica ligustilide in order, stirring for 20-40 min with a speed being 20-25 r / min to form jelly, allowing the jelly to stand for 7-9 h, sieving with a sieve having a size of 70-90 meshes, and forming through compression through a soft capsule production line. A prescription is formed through researching the encapsulated vagina cleaning liquid. The encapsulated vagina cleaning liquid is simple in formula, has good treating functions for viral infection of female genital tracts and has a good healthcare function for improving functions of female genital cavities.

The invention relates to a pharmaceutical composition for resisting cardiovascular diseases and combined by fish oil and rhizoma zingiberis recens extract. Shown by experimental study, the pharmaceutical composition has obvious effects for improving and treating diseases of a cardiovascular system. The pharmaceutical composition has the advantages that the used raw materials are wide in sources, natural and nontoxic, have less side effects and are lower in cost, so that the pharmaceutical composition has wide practical application value.

The invention discloses a multiple-effect polyclone antibody for animals, prepared according to the following method with steps of: A, adopting grouped poly immunogen polypeptide as immunogen, which at least contains the sequence of the immunogen polypeptides as shown in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, or a sequence with immunogenicity derived from the sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 by substituting, deleting, and / or adding one or more amino acid; B, immunizing animals: immunizing a target animal with the immunogen polypeptide of the step A and obtaining antiserum; and C, obtaining polyclone antibody: separating and purifying the antiserum immunoglobulin obtained in the step B to obtain the polyclone antibody. The polyclone antibody disclosed by the invention has extensive application in preparing integrate disease control drugs and immunopotentiating drugs for livestock.

The present invention involves the field of biomedical, and a whole -human source monoclonal antibody and its application of anti -new coronary virus are disclosed.Based on the receptor of the virus S protein as the probe, the memory B lymphocytes are used to screen the new coronary virus pneumonia patients with streaming cells, and the affinity constant of a single cloning antibody and RBD is 4.48 nm.The three -dimensional structure of the X -ray crystal diffraction antibody and the RBD complex found that the combination of antibodies and the host cell receptor (ACE2) of the host cells overlapped, which can competitively block the combination of RBD and ACE2, inhibit the virus infection of host cells.It can effectively respond to some genetic mutations in the new coronary virus, and half of the number of effective inhibitory concentrations that block the new coronary fake virus infection can reach a minimum of 20.93 ng / ml.Treatment and preventing new coronary virus pneumonia.

The invention discloses a multiple-effect polyclone antibody for animals, prepared according to the following method with steps of: A, adopting grouped poly immunogen polypeptide as immunogen, which at least contains the sequence of the immunogen polypeptides as shown in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, or a sequence with immunogenicity derived from the sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 by substituting, deleting, and / or adding one or more amino acid; B, immunizing animals: immunizing a target animal with the immunogen polypeptide of the step A and obtaining antiserum; and C, obtaining polyclone antibody: separating and purifying the antiserum immunoglobulin obtained in the step B to obtain the polyclone antibody. The polyclone antibody disclosed by the invention has extensive application in preparing integrate disease control drugs and immunopotentiating drugs for livestock.

The invention discloses an aromatic and appetizing traditional Chinese medicine sachet, which comprises the following components in parts by weight: 8-15 parts of cinnamon, 8-15 parts of cumin, 8-15 parts of cloves, 3-5 parts of Amomum, galangal 8 to 15 parts, 8 to 15 parts of calamus, 8 to 15 parts of tangerine peel, 8 to 15 parts of woodsy, 3 to 5 parts of Kou Ren, 8 to 15 parts of grass fruit, 8 to 15 parts of perilla leaves, 8 to 8 parts of perilla 15 servings. The fragrant and appetizing traditional Chinese medicine sachet of the present invention is inhaled through the mouth and nose with the taste of the medicine, so that the meridians are opened up, the pathogens are eliminated and the body is strengthened, so as to achieve the effect of dispelling diseases and strengthening the body. Traditional Chinese medicine has a wide range of therapeutic effects and can protect the stomach, especially to improve symptoms such as stomach pain and belching. After using traditional Chinese medicine to regulate qi and stomach, the effect is obvious and safe. The sachet uses a variety of fragrant medicinal materials, and the medicine in the sachet is distributed A persistent aromatic odor is emitted, inhaled into the respiratory tract, stimulates the mucous membranes of the human respiratory tract, and enables drug absorption to take effect.

The invention discloses a new application of 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinyl carboxy and derivatives thereof in the medicine field, namely an application in preparing a medicament for treating cystitis caused by chemotherapeutics. Found by the inventors surprisingly under study, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinyl carboxy and derivatives thereof have an amazing therapeutic action on treating the cystitis caused by chemotherapeutics, and are favorable for alleviating pain of patients taking chemotherapy and for improving the tolerance dose of the patients on the chemotherapeutics, so that the tetrahydropyrimidine and derivatives thereof can be used for preparing the medicament for treating cystitis caused by chemotherapeutics. The invention also provides a medicament for treating cystitis caused by chemotherapeutics, composed of the tetrahydropyrimidine or the derivatives thereof and medically acceptable pharmaceutical auxiliary materials. Compared with the existing medicaments such as mesna and the like, the tetrahydropyrimidine and derivatives thereof have extensive therapeutic actions on the cystitis caused by chemotherapeutics rather than have limited preventive actions.

The present invention relates to the technical field of food processing and particularly to an alcoholism-preventing and liver-protecting milk tablet and a preparation method thereof. The milk tabletcomprises the following raw materials in parts by weight: 3-7 parts of milk powder, 0.5-1.5 parts of a semen hoveniae extract, 1-5 parts of lemon juice, 0.005-0.02 part of vitamin B1, 0.5-2 parts of maltodextrin and 0.5-2 parts of sucrose. The milk powder has effects of benefiting the stomach, supplementing deficiency, promoting salivation, moistening dryness, and removing toxins; the semen hoveniae extract has functions of preventing alcoholism, quenching thirst, relieving restlessness, causing diuresis and protecting liver; the lemon juice has functions of promoting salivation and quenchingthirst, and strengthening the stomach and stopping pains and at the same time can improve mouthfeel of the milk tablet; and the vitamin B1 can accelerate alcohol metabolism process, eliminate free radicals produced in an ethanol metabolism process, reduce liver load, and achieve a purpose of protecting the liver. Therefore, the prepared milk tablet can effectively relieve symptoms of dizziness, vomiting, etc. caused by drinking wine, has effects of benefiting the stomach, relieving toxins and protecting the liver, the raw materials are also easy to obtain, the preparation method is simple, andthe product is convenient to eat and cheap in price.

The invention relates to a copper abietate raw drug and a preparation method thereof; the copper abietate raw drug comprises the following components in parts by weight: 10-80 parts of rosin, 1-40 parts of inorganic copper, 1-40 parts of an organic acid, 2-50 parts of an organic solvent, and 0.01-0.5 part of a catalyst. The preparation method comprises the steps: mixing evenly 10-80 parts by weight of the rosin, 2-50 parts by weight of the organic solvent and 1-40 parts by weight of the organic acid, adding into a sealed reaction kettle with a vacuum reflux unit, heating and stirring, after the rosin is completely dissolved, adding 1-40 parts by weight of inorganic copper, then adding 0.01-0.5 part by weight of the catalyst, heating up and carrying out a refluxing reaction, recycling a reflux condensed fluid, discharging, and cooling to obtain the copper abietate raw drug. The copper abietate raw drug obtained by adopting the copper abietate raw drug synthesis formula and the preparation method has the advantages of being high in content, suitable for preparation of a variety of forms of copper abietate bactericide products and the like.

The invention relates to a kidney-tonifying Xiezhuo Qiangjing pill and its preparation method and use method. The raw materials are composed as follows in parts by weight: 25-35 parts of Coix seed, 12-18 parts of Poria cocos, 12-18 parts of Scrophulariaceae, wheat 12‑18 parts of winter, 12‑18 parts of raw land, 12‑18 parts of Qumai, 12‑18 parts of Chinese herbal medicine, 6‑12 parts of plantain seed, 12‑18 parts of medlar, 12‑18 parts of dodder seed, 12‑18 part of Polygonum cuspidatum 15-25 parts of fairy spleen, 12-18 parts of Codonopsis pilosula, 9-15 parts of raw malt, 3-9 parts of licorice. The invention is a pure traditional Chinese medicinal preparation, which can invigorate the kidney and essence, diuresis and relieve turbidity, replenish qi and invigorate the spleen, and has the characteristics of extensive therapeutic effect, obvious effect, stable curative effect and no side effect.

Virtual reality system transposes a user's position and movement in real space to virtual space. The virtual reality system includes a locomotion interface that outputs signals indicative of a user's position in real space. The locomotion interface includes a pressure-sensing mat having a base layer, a plurality of pressure sensing elements and a counter-force generating layer formed over the base layer, and a top layer formed over the plurality of pressure-sensing elements. The plurality of pressure sensing elements output a signal indicative of pressure applied to the top layer. A virtual reality processor uses the signals output by the locomotion interface to produce an output indicative of the user's position in the virtual space corresponding to the user's position and movement in the real space. A display uses the output from the virtual reality processor to produce an image of the virtual space.