Magnetic separator and analyzer using the same

A magnetic separator and magnet technology, applied in magnetic separation, open gradient separator, solid separation, etc., can solve problems such as ambiguity, and achieve the effect of shortening the measurement time

Inactive Publication Date: 2008-09-03
HITACHI HIGH-TECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is still no clear theory as to how to set a better magnetic field distribution to uniformly capture magnetic particles floating near the container wall next to the magnet, or particles floating near the center of the container at the farthest position from the magnet.

Method used

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  • Magnetic separator and analyzer using the same
  • Magnetic separator and analyzer using the same
  • Magnetic separator and analyzer using the same

Examples

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Embodiment Construction

[0020] The magnetic separator of the present invention can be effectively used in a reaction vessel or tube in which a sample, magnetic particles, an antibody that binds the magnetic particles to an object to be measured in the sample, and a labeled antibody containing a labeling substance are mixed in a reaction container or a tube. Antigen-antibody reaction is carried out, and the mixed solution containing the reactive organisms in the sample that combines the object of measurement with magnetic particles and labeling substances is separated into reaction products and non-magnetic components that cannot be captured by magnetic force using a magnetic separation member In the automatic analysis device of the magnetic separator. The sample contained in the above-mentioned mixed solution contains impurities that are the main factor for lowering the analysis accuracy. Therefore, by separating non-magnetic components including reaction products and impurities with a magnetic separ...

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Abstract

The invention relates to a magnetic separator and an analyzer using thereof, with the aim that, the analyzer which collects magnetic particles for immunological analysis includes a magnetic separator adapted to efficiently separate within a short time a reaction product formed by bonding substances such as an object to be measured and the magnetic particles, and a nonmagnetic component other than the reaction product, from a liquid mixture in a vessel of the magnetic separator to perform the separation, a magnet complex having multiple magnets and magnetic materials stacked in alternate form so that magnetic pole pieces on opposed sides of each magnet are homopolar, is disposed outside the vessel that holds a liquid in which the magnetic particles are suspended.

Description

technical field [0001] The present invention relates to a magnetic separator for collecting magnetic particles floating in a container and an analysis device using the same, and more particularly to a magnetic separator with higher collection efficiency than conventional products and an analysis device using the same. Background technique [0002] Devices that apply a magnetic field to magnetic particles dispersed in a medium and collect them are used in various analyses, but an immunoassay device that measures the presence or absence and amount of antigens and antibodies in living samples such as blood will be described as an example. current technology. [0003] As a method of immunological analysis, it is known that in the analysis process, the antibody bound to the measurement object in the sample by magnetic particles and the labeled antibody containing the labeling substance are reacted in a reaction container for antigen-antibody reaction, and separated by magnetic fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B03C1/28B03C1/035G01N33/543
CPCB03C1/288B03C2201/18B03C2201/26
Inventor 有贺洋一山崎创铃木贯太郎
Owner HITACHI HIGH-TECH CORP
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