104results about "Open gradient mangetic separators" patented technology

A micro flow system is provided for separating particles, comprising a microfabricated member having a flow channel (5) defined therein for guiding a flow of a fluid containing the particles through the flow channel, first inlet means (2) positioned at one end of the flow channel for entering the fluid into the flow channel, first outlet means (7) positioned at the other end of the flow channel for discharging the fluid from the flow channel, the flow of the fluid containing the particles being controlled in such a way that one particle at the time passes a cross section of the flow channel, the member being positioned in a field that is substantially perpendicular to a longitudinal axis of the flow channel so that particles residing in the flow channel and being susceptible to the field across the flow channel are deflected in the direction of the field. Further, a micro flow system is provided for analyzing components of a fluid comprising a microfabricated member having a flow channel defined therein for guiding a flow of a fluid through the flow channel, first inlet means for entering particles into the flow channel, first outlet means for discharging of fluid from the flow channel and a plurality of assay sites located in the flow channel and comprising immobilized reagents whereby the fluid may be analyzed for a plurality of components while residing in the flow channel.

A device for transporting magnetic or magnetisable microbeads (25) in a capillary chamber (14) comprises a permanent magnet (10) or an electromagnet (11) for subjecting the capillary chamber to a substantially uniform magnetic field, to apply a permanent magnetic moment to the microbeads (25). At least one planar coil (22) and preferably an array of overlapping coils are located adjacent to the capillary chamber (14) for applying a complementary magnetic field on the microbeads parallel or antiparallel to said substantially uniform magnetic field, to drive the microbeads. An arrangement is provided for switching the current applied to the coil(s) (22) to invert the field produced thereby, to selectively apply an attractive or repulsive driving force on the microbeads (25). The device is usable to transport microbeads for performing chemical and biochemical reactions or assay, as is done for instance in clinical chemistry assays for medical diagnostic purposes.

A micro flow system is provided for separating particles, comprising a microfabricated member having a flow channel (5) defined therein for guiding a flow of a fluid containing the particles through the flow channel, first inlet means (2) positioned at one end of the flow channel for entering the fluid into the flow channel, first outlet means (7) positioned at the other end of the flow channel for discharging the fluid from the flow channel, the flow of the fluid containing the particles being controlled in such a way that one particle at the time passes a cross section of the flow channel, the member being positioned in a field that is substantially perpendicular to a longitudinal axis of the flow channel so that particles residing in the flow channel and being susceptible to the field across the flow channel are deflected in the direction of the field. Further, a micro flow system is provided for analyzing components of a fluid comprising a microfabricated member having a flow channel defined therein for guiding a flow of a fluid through the flow channel, first inlet means for entering particles into the flow channel, first outlet means for discharging of fluid from the flow channel and a plurality of assay sites located in the flow channel and comprising immobilized reagents whereby the fluid may be analyzed for a plurality of components while residing in the flow channel.

Separation apparatus and method for separating magnetic and / or magnetically-labeled particles from a test medium.Test medium within a reaction chamber is caused to flow past a collecting surface, and a high-gradient magnetic field is applied to the surface to capture magnetically responsive particles in the test medium. The particles are deflected toward the collection surface by baffles, a spinner, or a sprayer, or are funneled past the surface by a plunger operable to be displaced into close proximity to the surface to provide a narrow flow path for the particle-laden test medium. The particles normally suspended in the medium are separated out of suspension by adhesion to the collection surface. The particles may be resuspended by removal of the surface from the high-gradient field, or removal of the high-gradient field from the surface. The collection surface is a thin-walled non-magnetic material having a plurality of magnetic pole faces positioned therearound.

A method, system, apparatus, and article of manufacture provide a cross-flow migration classifier capable of separating particles. The classifier provides a channel through which a sample, having one or more particles, passes in a first direction, wherein the channel comprises two or more walls that are permeable to a flow of fluid. A cross-flow enters the channel through one of the permeable walls and exits through another of the permeable walls. An imposed field is applied in a second direction that is counter to the cross-flow and having an orthogonal component to the first direction. The imposed field causes one or more of the particles to migrate at a first velocity opposite and / or equal to a second velocity of the cross-flow. The particles that migrate opposite to the cross-flow are continuously discharged from the cross-flow migration classifier.

A method and apparatus for magnetically separating target particles of a selected type from a sample in order to produce a concentration of the target particles in the sample, or a depletion of the sample with respect to the target particles, by producing a sample mixture of the sample with magnetic particles having a selective affinity to magnetically stain the target particles; producing a flow of a buffer liquid through a tube which includes an inlet connectable to a source of buffer liquid, and an outlet for the buffer liquid; after a flow of the buffer liquid has been produced through the tube, introducing the sample mixture into the buffer liquid flowing through the tube such that the buffer liquid forms a continuous liquid carrier for the sample mixture as both are fed through the tube; and applying a magnetic field across the tube at a magnetizing station therein to cause the magnetically-stained target particles to be separated and retained in the buffer liquid within the tube at the magnetizing station.

The invention includes devices and methods for forming random arrays of magnetic particles, arrays formed using these devices and methods, and to methods of using the arrays. The invention provides an assembly (chip) with magnetic domains that produce localized magnetic fields capable of immobilizing magnetic particles such as commercially available magnetic beads. Probe or sensor molecules can be coupled to the beads, which are then dispersed on the assembly, forming a random order array. The arrays can be used for analyzing samples, targets, and / or the interaction between samples and targets. The invention finds particular use in processes such as high-throughput genotyping and other nucleic acid hybridization-based assays.

PCT No. PCT / FR97 / 00794 Sec. 371 Date May 15, 1998 Sec. 102(e) Date May 15, 1998 PCT Filed May 5, 1997 PCT Pub. No. WO97 / 42503 PCT Pub. Date Nov. 13, 1997A process for magnetic immunoseparation of cells, in particular bacteria, fetal cells, stock cells of bone marrow and circulating cancerous cells, of the type consisting in affixing the target cells on paramagnetic balls and in causing a magnetic field to act on a sample containing the affixed cells, the free cells and the surplus paramagnetic balls, in order to isolate the paramagnetic balls, in that the sample is caused to circulate in a tube the section of which is much less than the length over which the magnetic field is applied.

System and method for providing a sample preparing arrangement (10) submergible in a liquid medium that includes a carrier structure (11) having at least one cavity (12) therein and that is in communication with an arrangement (13) for controllable generation of a magnetic field through influence of a control signal. The sample preparing arrangement includes a magnetic covering structure (14) for covering and / or uncovering the cavity in operative interaction with the magnetic field.

A laminar or cyclonic particle separator for gas, liquid-liquid and fluidizable solids separation comprised of a section with a non-metallic housing having an annulus and a chamber, an optional anode cooled with a first coolant in and a first coolant out disposed in the chamber, a DC or pulsating DC power source connected to the anode, at least one magnetic coil disposed adjacent the chamber and cooled with a second coolant, a high voltage pulsating DC power source connected to the magnetic coil, and a fluid (gas, liquid or fluidizable solids) inlet port connected to the housing, and also a section with a non-metallic separator tube connected to the housing and disposed within the housing, a first fluid outlet connected to the annulus through the housing. This device can then separate a stream rich in a targeted element (first fluid) and a stream lean in a targeted element (second fluid) from the device and thus discharge a stream almost free of the targeted element or almost 100% the targeted element.

Method and arrangement (10, 20) for preparing samples (15, 27) submergible in a liquid medium. The arrangement includes a carrier structure (11). The carrier includes a device (13, 23) for controllable generation of a magnetic field through influence of a control signal to attract at least part of the at least first and second type of samples (15, 27) towards specific locations on the carrier when connected to a first control signal and to repel at least one of the first or second type of samples when connected to a second control signal.

Systems and methods for removing hydrocarbons and other pollutants from roadway surfaces are provided. The systems can include a pollution trap attached to a vehicle, where the pollution trap comprises an absorbent pad, filter, or membrane. The pollution trap is affixed to the vehicle, for example, in the wheel well, on a mud flap, on the underside of a vehicle or another suitable place where the pollution trap can be exposed to a roadway pollutant. The methods described herein can include liberating roadway pollutants from a roadway and using a pollution trap to collect the liberated roadway pollutants.

A method for separating inclusions from an electrically conductive liquid flow using electromagnetic forces, wherein the inclusions and the liquid have differing electrical conductivities. The flow is exposed to a spatially heterogeneous magnetic flux produced by a continuous static magnetic field.

Systems and methods for removing hydrocarbons and other pollutants from roadway surfaces are provided. The systems can include a pollution trap attached to a vehicle, where the pollution trap comprises an absorbent pad, filter, or membrane. The pollution trap is affixed to the vehicle, for example, in the wheel well, on a mud flap, on the underside of a vehicle or another suitable place where the pollution trap can be exposed to a roadway pollutant. The methods described herein can include liberating roadway pollutants from a roadway and using a pollution trap to collect the liberated roadway pollutants.

An object of the invention is to provide a wastewater treatment system using a superconducting magnetic separator that can wash the magnetic filter efficiently. The system comprises in a bore of a superconducting magnet a removably built-up multiunit magnetic filter consisting of a plurality of single-unit magnetic filters. The multiunit magnetic filter has a total longitudinal length at least equal or greater than that of the superconducting magnet. During excitation of the superconducting magnet, a single-unit magnetic filter is removed from the upstream side (sewage side) of the multiunit magnetic filter by pushing in another single-unit magnetic filter from the downstream side (clean water side), and washed and returned to the downstream side again.

An apparatus for retaining magnetic particles within a segment of a flow-through cell during flow of a fluid through the cell comprises (a) optionally, an electrical current source; (b) an electromagnet having a winding connected to the current source and an air gap between at least one pair of poles each of which has a corrugated outer surface and (c) a flow-through cell which is configured and dimensioned to receive an amount of magnetic particles to be retained within the flow-through cell and to allow flow of a liquid through the flow-through cell. The liquid carries molecules or particles to be captured by means of the magnetic particles. A portion of the flow-through cell is inserted in air gap.

The invention discloses a strong magnetic iron remover with low temperature superconductivity, a cryostat is arranged on an outer cover of the invention, and the cryostat is hoisted on an inner wall of the outer cover through a pull-rod. The cryostat is provided with an indoor temperature Dewar, a 4.2K Dewar is arranged in the indoor temperature Dewar, a heat radiation screen is arranged between the indoor temperature Dewar and the 4.2K Dewar, gaps are arranged in perimeters between the indoor temperature Dewar and the heat radiation screen and between the heat radiation screen and the 4.2K Dewar, a superconducting coil can be coiled in insulation on an inner cylinder of the 4.2K Dewar, and power can be provided for the superconducting coil by a pair of two-dimensional electric currents lead-in wires. A vacuum state is between the indoor temperature Dewar and the 4.2K Dewar, and the 4.2K Dewar is filled with liquid helium20. The invention has great magnetic induction intensity, and can suck out tiny iron magnetic substances from materials, and has high working stability.

A device for transporting magnetic or magnetizable microbeads (25) in a capillary chamber (14) comprises a permanent magnet (10) or an electromagnet (11) for subjecting the capillary chamber to a substantially uniform magnetic field, to apply a permanent magnetic moment to the microbeads (25). At least one planar coil (22) and preferably an array of overlapping coils are located adjacent to the capillary chamber (14) for applying a complementary magnetic field on the microbeads parallel or antiparallel to said substantially uniform magnetic field, to drive the microbeads. An arrangement is provided for switching the current applied to the coil(s) (22) to invert the field produced thereby, to selectively apply an attractive or repulsive driving force on the microbeads (25). The device is usable to transport microbeads for performing chemical and biochemical reactions or assay, as is done for instance in clinical chemistry assays for medical diagnostic purposes.

There is provided a method for purifying carbon filamentary structures contaminated with magnetic metal particles. The method comprises submitting a gaseous phase comprising said carbon filamentary structures contaminated with magnetic metal particles, to an inhomogeneous magnetic field for at least partially trapping said magnetic metal particles, thereby reducing the proportion of said magnetic metal particles present in said gaseous phase. The method is particularly useful for purifying carbon filamentary structures such as multi-wall carbon nanotubes, single-wall carbon nanotubes or carbon fibers. An apparatus for purifying such carbon filamentary structures contaminated with magnetic metal particles is also provided.

The invention relates to a magnetic separator and an analyzer using thereof, with the aim that, the analyzer which collects magnetic particles for immunological analysis includes a magnetic separator adapted to efficiently separate within a short time a reaction product formed by bonding substances such as an object to be measured and the magnetic particles, and a nonmagnetic component other than the reaction product, from a liquid mixture in a vessel of the magnetic separator to perform the separation, a magnet complex having multiple magnets and magnetic materials stacked in alternate form so that magnetic pole pieces on opposed sides of each magnet are homopolar, is disposed outside the vessel that holds a liquid in which the magnetic particles are suspended.

The invention relates to a magnetic separation device and is used for separating paramagnetic substances from diamagnetic substances, the paramagnetic substances according to the paramagnetic susceptibility thereof and the diamagnetic substances according to the diamagnetic susceptibility thereof. Said invention can be used for electronics, metallurgy and chemistry, for separating biological objects and for removing heavy metals and organic impurities from water, etc. The inventive device is based on a magnetic system of an open domain structure type and is embodied in the form of two substantially rectangular constant magnets (1, 2) which are mated by the side faces thereof, whose magnetic field polarities are oppositely directed and the magnetic anisotropy is greater than the magnetic induction of the materials thereof. Said magnets (1, 2) are mounted on a common base (4) comprising a plate which is made of a non-retentive material and mates with the lower faces of the magnets, thin plates (5, 6) which are made of a non-retentive material, are placed on the top faces of the magnets and forms a gap arranged above the top edges (8, 9) of the magnets (1, 2) mated faces. A nonmagnetic substrate (10) for separated material (11) is located above the gap (7).

This embodiment of a magnetic separation device has: a plurality of magnetic separation columns of which a plurality are disposed in series and that have a plurality of filters comprising a non-magnetic cylinder of which the hollow center is the flow path for water to be processed, and a magnetic body disposed in a manner so as to be perpendicular to the flow of water to be processed within the cylinder; and a magnetic field imposition device that imposes a magnetic field to a portion of the magnetic separation columns, has a size that corresponds to the portion of magnetic separation columns, and is provided slidably to the outside of the plurality of magnetic separation columns.

A magnetic separator vessel (1) for separating magnetic particles from non-magnetic fluid includes a separation chamber having an interior and exterior wall, a top and bottom portion; a magnet (3) having first and second poles (2) positioned adjacent to the exterior wall, wherein the first pole is substantially diametrically opposed to the second pole; a inlet port (5) is directed into the top portion of the separation chamber, wherein the inlet port (5) is positioned adjacent to one of the first and second poles (2), wherein the inlet port (5) is adapted to transfer a mixture into the separation chamber; an underflow port (6) in communication with the bottom portion, wherein the underflow port (6) is adapted to receive the magnetic particles; and an overflow port (9) in communication with the separation chamber, wherein the overflow port (9) is adapted to receive the non-magnetic fluid.

The invention discloses a high temperature superconductive electromagnetic deironing element, which comprises the following parts: superconducting magnet, programmed power and magnetic control computer (1), wherein the screwed pipe coil axle of vertical and horizontal superconductive magnet (4, 5) is perpendicular with power supplied by two programmed energy (2, 3); the spatial working magnetic field is formed in the magnetic shaft plane; the liquid nitrogen container (12) lies between low-temperature container (17) and thermal radiation screen (16), which is assembled on the thermal radiation screen (16); the thermal radiation screen (16) is suspended in the low-temperature container (17); the nitrogen fixation container (15) is loaded in the thermal radiation screen (16); the disc-type windings (14) is assembled in the nitrogen fixation container (15); the serial port of computer (1) is controlled by magnetic field to connect serial ports of two programmed superconductive powers (2) and (3), which can adjust the powers (2) and (3) to control the direction and strength of working spatial magnetic field.

The present invention discloses a system for separating minerals in drilling fluid based primarily on density. The separator creates and maintains a slurry with a controllable density for separating minerals from drill cuttings. The density if controlled through the use of an electrode array. The separator comprises a primary separation chamber containing the dense slurry, and a multiple number of secondary separation chambers used to separate cuttings from the drilling fluid. The invention also contains inlet hardware allowing the mixed mineral suspension to enter the first separation chamber, and hardware allowing the three outlet (separated) streams to exit the device. One of the three outlet streams carries the minerals that have a density greater than the user selectable density set point, while the second carries the minerals that have a density less than the density set point, and the third carries clean drilling fluid.

A microfluidic separation system, which comprises a magnetic separator, which itself comprises a magnetic energy source; first and second magnetically conductive members leading from the magnetic energy source and having respective terminal ends that are separated by a gap over which a magnetic field is applied due to the magnetic energy source. The separation system further comprises a microfluidic chip for insertion into the gap, which comprises a body defining channels on respective faces of the body; and an exterior lining that seals the plurality of channels to allow separate test sample volumes to circulate in at least two of the channels. Upon insertion of the chip into the gap, a first test sample volume is confined to circulating closer to the terminal end of the first member and a second test sample volume is confined to circulating closer to the terminal end of the second member.

The invention relates to a method and device for separating magnetic particles, for separating magnetic particles from a sample housed in an inner space (1) of the separating device. In accordance with the invention, the magnetic field is generated with a specific configuration of the magnets (3). This specific configuration enables devices of different sizes with a reduced number of magnets or types of magnets to be established.