Method and apparatus for ionizing mass spectrographic analysis sample

A mass spectrometry and ionization technology, applied in mass spectrometers, measuring devices, analytical materials, etc., can solve the problems of mass spectrometry detection of neutral substances and few reports of neutral substances, and achieve the effect of simple structure and convenient operation

Inactive Publication Date: 2008-10-08
FUDAN UNIV
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Problems solved by technology

Neutral species produced by these electrospray ionization processes cannot be detected by mass spectrometry because they have

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  • Method and apparatus for ionizing mass spectrographic analysis sample
  • Method and apparatus for ionizing mass spectrographic analysis sample
  • Method and apparatus for ionizing mass spectrographic analysis sample

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Abstract

The invention belongs to the field of analysis technology, particularly an ionization method for mass spectrum analysis of samples and the apparatus thereof. The method of the invention includes: firstly generating plasma with the method of gas dielectric barrier discharge, then causing the plasma to generate collision with neutral sample molecules which are generated in the course of electrospray ionization, so that the neutral sample molecules generate ionization to become ions which are provided for the following mass spectrum analysis. The apparatus of the invention comprises an electrospray ionization ion source device, a dielectric barrier discharge pipe, a couple of ion deflection electrode devices, and a vacuum chamber for sample molecular ionization, wherein the neutral sample molecules and the ions generated by the dielectric barrier discharge ionization generate charge transfer reaction to generate sample ions. The apparatus has simple structure and convenient operation, which enables the neutral sample molecules generated by the electrospray ionization ion source device to be detected with mass spectrum method.

Description

technical field [0001] The invention belongs to the technical field of analysis, and in particular relates to a novel mass spectrometry sample ionization method and a device thereof. technical background [0002] As a modern analytical instrument, mass spectrometer is widely used in scientific research, technology development and daily production and life. For example, physicists and chemists often use mass spectrometers to analyze the type, structure and content of substances, and biologists often use mass spectrometers to study the structure and function of living substances. Mass spectrometers can also be used to analyze the composition of food and the composition of materials, and to detect pollution in the atmosphere and water sources. In short, the mass spectrometer has become one of the indispensable scientific instruments in modern society. [0003] As an important part of the mass spectrometer, the research and development of the ion source has received extensive ...

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Application Information

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IPC IPC(8): G01N27/64H01J49/26
Inventor 杨鹏蒋公羽李周李晓旭丁传凡
Owner FUDAN UNIV
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