Novel electric spray sample introduction vacuum ultraviolet single photon ionization mass spectrum analysis apparatus

Abstract

The invention relates to a novel electro-spray sampling vacuum ultraviolet single-photon ionization mass spectrometry analysis device which solves the analysis problems of a plurality of non-polarity composition complex systems. The device of the invention comprises a photoionization chamber and a differential chamber which are adjacent to each other; the adjacent side walls of the photoionization chamber and the differential chamber are communicated with a perforated ladle which is convex towards the differential chamber; the outlet of the perforated ladle is corresponding to the middle of the lead-out electrode and acceleration electrode of a time-of-flight mass spectrometer; the inlet of the perforated ladle is corresponding to an inverted horn-shaped nozzle on the side wall of the differential chamber; the inlet of the perforated ladle is in inverted horn shape; an electro-spray needle corresponding to the nozzle is arranged outside the differential chamber; the other end of the electro-spray needle is connected with an injection pump. The device of the invention combines the electro-spray sampling and vacuum ultraviolet photoionization mass spectrometry technique, directly sprays the sample to be measured out of the electro-spray needle during the testing and analysis process, and requires no complex pre-processing and separation of the sample; as the electro-spraying has no restrictions on the thermal stability and volatility of the sample, the device of the invention can be widely applied to the analysis and detection of simple organic matters and complex organic mixtures and can monitor certain organic reaction processes in real time.

Description

technical field

[0001] The invention relates to an analysis device for real-time detection of complex natural products, complex organic mixtures, organic reaction products and intermediates, specifically a photon ionization mass spectrometry analysis device. Background technique

[0002] Mass spectrometry is an important method for identifying molecular structures. According to the structure and properties of the analyte, there are various kinds of mass spectrometry sampling, separation systems, ionization techniques and mass analyzers. In 1984, Yamashita and Fenn invented electrospray ionization mass spectrometry (ESI-MS) based on the work of their predecessors. The technology is to pass the solution to be tested through a capillary with high voltage under atmospheric pressure, and generate highly charged mist droplets under the action of an electric field of 2-6KV. During the migration process, the mist droplets will gradually decrease due to solvent evaporation or Coulo...

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