Configurable, flexible apparatus and method for personal health monitoring and delivery

Abstract

The present invention generally relates to a system and method that co-locates in a small flexible, configurable system and multi-level substrate sampling, rapid analysis, bio-sample storage and delivery functions to be performed on living tissues or matter obtained from living organisms. The types of the sampling may include chemical, biochemical, biological, thermal, mechanical, electrical, magnetic and optical sampling. In general, the analysis performed at the point of sampling measures the sample taken and records its value. The bio-sample storage function encapsulates a small sample of analyte and preserves it for subsequent examination or analysis, either on the organism by the system or at a remote location by an independent analysis system. Once stored, the sample can provide a record of a biological state at the precise time of sampling. The delivery at the point of sampling can include chemical, biochemical, biological, thermal, mechanical, electrical, magnetic and optical stimuli.

Description

[0001] Cross References to Related Applications [0001] This application is related to and claims priority from International Patent Application No. PCT / US 2005 / 044287, filed December 9, 2005, entitled "Apparatus and Method for Continuous Real-Time Trace Biomolecular Sampling, Analysis and Delivery", which claims Priority to U.S. Provisional Patent Application No. 60 / 634,783, filed December 9, 2004, entitled "Systems and Methods for Monitoring Health and Delivering Drugs Transdermally," both documents are hereby incorporated by reference in their entirety. field of invention [0002] The invention relates to portable biomedicine and biomolecular monitoring, remote diagnosis and related health care fields. More specifically, the present invention relates to methods, devices and systems for configurable flexible personal health monitoring and material delivery systems. Background of the invention [0003] Non-invasive percutaneous sampling of body fluids has long been a goal...

AI Technical Summary

Problems solved by technology

[0006] Also, microfabrication of complex systems often requires the use of silicon substrates, which are relatively inflexible, making tight surface contact difficult and causing lateral movement between the transcutaneous monitor and the hole through the stratum corneum

Since the size of the percutaneous holes is typically tens of microns in diameter, even small amounts of sideways movement can render the device ineffective

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