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Epithelial pocket expanding tool and combination epithelial delaminating device and corneal reformer

A technology of epithelial bags and epithelial tissue, which is applied in ophthalmic surgery and other fields, and can solve problems such as infection breeding, performance damage, and impermeability

Inactive Publication Date: 2009-02-18
TISSUE ENG REFRACTION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are several problems with epikeratophakia: 1) the lens remains hazy until host stromal fibroblasts colonize the lens, which can take months; 2) the migrating epithelium is able to grow over the incision site Interrupted epithelium is a breeding ground for infection before onto the surface of the lens; and, 3) Healing of the epithelium onto the surgical site sometimes migrates into the space between the lens and the host cornea
However, this "bandage" fails to restore the epithelium to its original state, i.e., it does not maintain the integrity of the epithelium, thereby reducing its clarity, water impermeability and barrier function
In addition, the ability of the epithelium to adhere to the surface of the corneal stroma is impaired

Method used

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  • Epithelial pocket expanding tool and combination epithelial delaminating device and corneal reformer
  • Epithelial pocket expanding tool and combination epithelial delaminating device and corneal reformer
  • Epithelial pocket expanding tool and combination epithelial delaminating device and corneal reformer

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Embodiment Construction

[0043] For any bodily surface, such as skin, respiratory epithelium, intestinal epithelium and cornea, there is a layer of epithelial cells adhered to the underlying basement membrane. Subepithelial blisters form when the epithelium separates from its basement membrane and underlying collagenous tissue. In general, gross separations less than 1 mm in diameter are referred to as vesicles and separations greater than 1 mm in diameter are referred to as euvesicles.

[0044] The continuous corneal epithelial layer may be separated from the anterior surface of the eye by applying various mechanical forces to the anterior surface or to the basal cell layer or to the junction of the basal cell layer and Bowman's layer or membrane (the "transparent layer") or mention. The term "continuous" as used herein means "uninterrupted". The term "mechanical force" as used herein refers to any physical force produced by a person, instrument or device. Examples of mechanical forces include suc...

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PUM

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Abstract

The described devices are useful in the field of ophthalmology. The devices and methods for using them involve separating or lifting corneal epithelium from the eye in a substantially continuous layer to form a flap or pocket. In particular, the devices generally utilize a non- cutting separator or dissector that is configured to separate the epithelium at naturally occurring cleavage surfaces in the eye, particularly between the epithelium and the corneal stroma (Bowman's membrane), specifically separating in the region of the lamina lucida. The dissector may oscillate during the noted separation. The separator or dissector may also have a structure that expands the epithelial pocket after formation. Independently, the separator or dissector may also include structure that alone or in combination with various energy sources, reforms the underlying cornea in a refractive procedure or treats other maladies. After such steps, the epithelium tissue member may then be replaced on the cornea or onto an ocular lens after placement of that ocular lens on the eye.

Description

technical field [0001] The device is suitable for use in the field of ophthalmology. These devices and methods of using these devices involve separating or lifting the corneal epithelium from the eye in a substantially continuous layer to form a flap or pocket. In particular, these devices typically utilize non-cutting separators or dissectors that are configured to separate the epithelium at the natural cleavage surface in the eye, particularly between the epithelium and the corneal stroma ( Bowman's membrane), in particular in the region of the lamina lucida. The dissector may oscillate during said separation. The separator or dissector may also have a structure that expands the epithelial pocket after formation. The separator or dissector may also independently include a structure that alone or in combination with various energy sources remodels the underlying cornea during refractive procedures or treatment of other diseases. After these steps, the epithelial tissue po...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/013
CPCA61F9/0133A61F9/013
Inventor E·佩雷斯E·T·惠洛克
Owner TISSUE ENG REFRACTION
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