Cell analyzer and cell analyzing method

An analysis method and technology of an analyzer, which are applied in the field of cell analyzers and cell analysis, and can solve problems such as difficulty in measuring cells

Active Publication Date: 2009-04-08
SYSMEX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is difficult to accurately measure cells with a size of 20 to 100 μm such as the epithelial cells of the cervical region with the analyzer disclosed in the above-mentioned U.S. Patent No. 5,050,987

Method used

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  • Cell analyzer and cell analyzing method
  • Cell analyzer and cell analyzing method
  • Cell analyzer and cell analyzing method

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Embodiment Construction

[0032] Embodiments of the cell analyzer and cell analysis method of the present invention will be described in detail below with reference to the drawings.

[0033] [Overall structure of cell analyzer]

[0034] FIG. 1 is a perspective explanatory view of a cell analyzer 10 according to an embodiment of the present invention. This cell analyzer 10 allows a measurement sample containing cells collected from a patient to flow through a flow cell, irradiates the measurement sample flowing through the flow cell with laser light, and detects and analyzes light emitted from the measurement sample (forward scattered light, side Fluorescence, etc.), to determine whether the above cells contain cancer and atypical cells. Specifically, the cell analyzer 10 is used to screen cervical cancer using epithelial cells of the cervical region. The cell analyzer 10 includes an instrument main body 12 for performing sample measurement, and a system control device 13 connected to the instrument m...

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Abstract

The present invention is to present a cell analyzer capable of measuring cells which are approximately 20 to 100 [mu]m in size with high precision via flow cytometry. The cell analyzer 10 comprises: a flow cell 51 in which a measurement sample including a measurement target cell flows; a light source part 53 for irradiating a light on the measurement sample flowing in the flow cell 51; an optical system 52 for forming a beam spot on the measurement sample flowing in the flow cell 51, the beam spot having a diameter of 3-8 [mu]m in a flow direction of the measurement sample and a diameter of 300-600 [mu]m in a direction perpendicular to the flow direction of the measurement sample; and a light receiving part 55, 58, 59 for receiving a light from the measurement sample.

Description

Technical field: [0001] The invention relates to a cell analyzer and a cell analysis method. More specifically, it relates to a cell analyzer and a cell analysis method for analyzing cells contained in a measurement sample by using light emitted from the measurement sample to illuminate a measurement sample flowing through a flow cell. Background technique: [0002] U.S. Patent No. 5,050,987 discloses an analyzer that uses flow cytometry to irradiate a measurement sample containing blood cells with laser light, and utilizes scattered light and fluorescence emitted by the measurement sample to measure leukocytes and leukocyte nuclei in blood. [0003] The flow cytometry technique disclosed in the aforementioned U.S. Patent No. 5,050,987 is used to measure leukocytes with a size of about 10 μm. It is difficult to accurately measure cells with a size of 20 to 100 μm, such as epithelial cells in the cervical region, using the analyzer disclosed in the aforementioned US Patent N...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N15/00G01N21/53G01N21/64C12Q1/02
Inventor 福田正和石坂正树
Owner SYSMEX CORP
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