Unlock instant, AI-driven research and patent intelligence for your innovation.

Inhibitor of increase in postprandial blood insulin level

A technology for insulin and inhibitors, applied in the field of insulin rise inhibitors

Inactive Publication Date: 2009-05-06
KAO CORP
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the relationship between monoacylglycerols and postprandial blood insulin concentrations is unknown

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Inhibitor of increase in postprandial blood insulin level
  • Inhibitor of increase in postprandial blood insulin level

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1 Inhibitory effect of mouse monoacylglycerol on post-diet blood insulin rise

[0032] Triolein was used as triacylglycerol, and 1-monoolein was used as monoacylglycerol.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention provides an agent for inhibiting a postprandial increase in blood insulin level, wherein the agent containing a monoacylglycerol as an active ingredient. An agent of the invention for inhibiting a postprandial increase in blood insulin level contains a monoacylglycerol as an active ingredient.

Description

technical field [0001] The present invention relates to a postprandial blood insulin rise inhibitor useful as medicine or food. Background technique [0002] After a meal, due to the rise in blood sugar, insulin is secreted from the pancreatic β cells of the pancreas, which promotes the intake of sugar in fat and muscle, promotes the synthesis of fat in the liver and muscle, and inhibits fat decomposition and burning. [0003] However, if insulin is continuously secreted in a hyperglycemic state, insulin sensitivity in skeletal muscle, liver, and adipose tissue, which are insulin target organs, decreases (insulin resistance), which further leads to more secretion of insulin from the pancreas. Such repeated insulin secretion eventually leads to pancreatic fatigue, decreased insulin secretion from pancreatic β cells, and increased insulin resistance in each target organ. It is known that the mechanism of action of insulin does not work well, resulting in a constitution prone ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/22A61K31/23A61P3/04A61P3/10
CPCA61K31/23A23L1/3008A61K31/22A23L33/12A61P3/04A61P3/10
Inventor 竹野菜奈美下丰留玲目黑真一
Owner KAO CORP