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Use of daphne primeverose-genkwanin and daphne plant

A technology of Rhizoma primrose and davidin, which can be applied in the directions of sugar derivatives, plant raw materials, medical preparations containing active ingredients, etc., can solve the problems of leukemia recurrence and the like

Inactive Publication Date: 2009-06-17
上海国源生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it has great risks, mainly in two points: one is that there are many transplant-related complications in HSCT, and the other is that there is still leukemia recurrence after HSCT: the main transplant-related complications are: hepatic veno-occlusive disease, and its incidence 25%, the mortality rate is 80%, graft versus host disease, the incidence rate is 10%-80%

Method used

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  • Use of daphne primeverose-genkwanin and daphne plant
  • Use of daphne primeverose-genkwanin and daphne plant
  • Use of daphne primeverose-genkwanin and daphne plant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Preparation of Whole Herb Powder I

[0081] Adopt Daphne odora Thunb whole herb of Phnom Penh Daphne odora Thunb, after being dried in the sun, through pulverizing into 100 mesh granules, whole herb powder I is obtained.

Embodiment 2

[0083] Preparing Whole Herb Powder II

[0084] The whole herb of Daphne genkwa Sieb.et Zucc was used, dried in the sun, and crushed into 100-mesh granules to obtain the whole herb powder II.

Embodiment 3

[0086] Preparation of Whole Herb Powder III

[0087] The whole herb of Daphne papyracea Wall.ex Steud. was used, dried in the sun, and crushed into 100-mesh granules to obtain the whole herb powder III.

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PUM

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Abstract

The invention discloses a Daphne primeverosyl-Genkwanine (DPG) of a formula I , or an alcohol extract of Daphne plants containing DPG of the formula I, or application of the Daphne plants containing DPG of the formula I to the preparation of medicines treating leukemia. The invention also provides a medicine composite containing DPG shown by the formula I.

Description

technical field [0001] The present invention relates to the field of plant medicine. More specifically, it relates to the use of Daphne primeverosyl-Genkwanine (Daphneprimeverosyl-Genkwanine, DPG) extracted from Daphne genus plants and Daphne genus plants. Background technique [0002] With the development and progress of medicine, the treatment level of leukemia has also been greatly improved. People are not only satisfied with the complete remission of the patient, but are committed to the research on the long-term disease-free survival and even recovery of the patient. Currently, the treatment methods for leukemia include chemotherapy. , integrated traditional Chinese and Western medicine, and hematopoietic stem cell transplantation. [0003] Chemotherapy is the use of chemical agents to kill leukemia cells, so that patients can achieve long-term survival and even cure. There are many types of leukemia, and different chemotherapy regimens should be selected for differen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H17/07A61K31/7048A61P35/00
CPCA61K36/83A61P35/00A61P35/02
Inventor 浦权黄文华
Owner 上海国源生物技术有限公司
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