Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Ceftibuten chewable tablet

A technology of ceftibuten and chewable tablets, which is applied in the field of ceftibuten chewable tablets, can solve problems such as inconvenience, and achieve the effect of high quality, good stability and simple method

Inactive Publication Date: 2009-07-01
BEIJING HOPE HUGE PHARM SCI
View PDF0 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the third-generation varieties need to be administered by injection, which is very inconvenient

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ceftibuten chewable tablet
  • Ceftibuten chewable tablet
  • Ceftibuten chewable tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: specification 1000 pieces

[0033] prescription:

[0034] Ceftibuten 200g 400g

[0035] Sucrose 180g 270g

[0036] Mannitol 250g 350g

[0037] Sodium chloride 10g 15g

[0038] Aspartame 1g 2g

[0039] Strawberry essence 0.4g 0.8g

[0040] Silica 1.5g 3g

[0041] Magnesium Stearate 3g 6g

[0042] 50% ethanol appropriate amount

[0043]

[0044] Preparation method:

[0045] Pass ceftibuten, sucrose, and mannitol through 80-mesh sieve respectively, weigh according to the prescription amount, mix evenly, dissolve sodium chloride in 50% ethanol to make soft material, granulate, dry at 60°C, granulate, and then add additional Excipients strawberry flavor, aspartame, silicon dioxide, magnesium stearate, mixed evenly, the intermediates are subpackaged after passing various quality inspections to obtain

Embodiment 2

[0046] Embodiment 2: specification 10000 pieces

[0047] prescription:

[0048] Ceftibuten 2000g 4000g

[0049] Sucrose 1800g 2700g

[0050] Mannitol 2500g 3500g

[0051] Sodium chloride 100g 150g

[0052] Aspartame 10g 20g

[0053] Strawberry essence 4g 8g

[0054] Silica 15g 30g

[0055] Magnesium Stearate 30g 60g

[0056] 50% ethanol appropriate amount

[0057]

[0058] Preparation method:

[0059] Pass ceftibuten, sucrose, and mannitol through 80-mesh sieve respectively, weigh according to the prescription amount, mix evenly, dissolve sodium chloride in 50% ethanol to make soft material, granulate, dry at 60°C, granulate, and then add additional Excipients strawberry flavor, aspartame, silicon dioxide, magnesium stearate, mixed evenly, the intermediates are subpackaged after passing various quality inspections to obtain

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of medicaments, a chewable tablet of ceftibuten is used for treating upper respiratory tract infections, such as pharyngitis, tonsillitis, scarlatina, parasinusitis and tympanitis; lower respiratory tract infections, such as acute bronchitis, acute onset of chronic bronchitis and pneumonia; urinary tract infection; enteritis and gastroenteritis. The novel dosage form is characterized in that the product is a chewable tablet chewed or sucked in the mouth to dissolve for administration, and to take effect in the gastrointestinal tract or in the whole body through the absorption of the gastrointestinal tract.

Description

technical field [0001] The invention belongs to the technical field of medicines. A ceftibuten chewable tablet is used for treating upper respiratory tract infections such as pharyngitis, tonsillitis, scarlet fever, paranasal sinusitis and otitis media; lower respiratory tract infections such as acute bronchitis, acute exacerbation of chronic bronchitis and pneumonia ; urinary tract infection; enteritis and gastroenteritis. Specifically, a ceftibuten chewable tablet. Background technique [0002] Cephalosporin antibiotics have the characteristics of broad antibacterial spectrum, strong antibacterial activity, high curative effect, and low toxicity, and have been widely used clinically. By 1998, 56 varieties including the first generation to the fourth generation were on the market in the world. Since the first-generation cephalosporin cephalothin was successfully developed in China in the 1970s, cephalosporin antibiotics have been greatly developed in China. In 2001, the sa...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/20A61K31/546A61P31/04
Inventor 王翰斌闫艳立吴广俣
Owner BEIJING HOPE HUGE PHARM SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com