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Medicament composition

A composition and drug technology, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of side effects and long-term application, and achieve the effect of improving production efficiency and saving costs.

Inactive Publication Date: 2009-08-05
SHENZHEN SANSHUN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Chronic cystic hyperplasia of mammary glands does not have a completely effective drug so far that can be completely treated. Some drugs can only improve or control local symptoms and signs. Treatment with western medicine such as: methyl testosterone, testosterone propionate, tamoxifen and other treatments, often Can bring certain side effects, can not be used for a long time

Method used

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  • Medicament composition
  • Medicament composition
  • Medicament composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Take 200 grams of Artemisia argyi, 85 grams of Epimedium, 85 grams of Asparagus, 85 grams of Bupleurum, 85 grams of Toosendan and 85 grams of Tu Fritillaria. Grind Bupleurum and Fritillaria into coarse powder, put them into an extraction tank, add 8 times the amount of water to soak for 1 hour, then put the other four herbs in, add water to decoct three times, add 8 times the water for the first time, Decoct for 1.5 hours, add 6 times the amount of water for the second and third times, and decoct for 1 hour; filter and combine the filtrates; concentrate the filtrates into extracts. The obtained extract is sprayed into the auxiliary material starch, sprayed and dried at an air inlet temperature of 70-160° C. and an outlet air temperature of 45-85° C. to obtain granules, compressed into tablets, and coated.

Embodiment 2

[0039] Take 200 grams of Artemisia argyi, 115 grams of Epimedium, 115 grams of Asparagus, 115 grams of Bupleurum, 115 grams of Toosendan and 115 grams of Fritillaria. Grind Bupleurum and Fritillaria into coarse powder, put them into an extraction tank, add 8 times the amount of water to soak for 1 hour, then put the other four herbs in, add water to decoct three times, add 8 times the water for the first time, Decoct for 1.5 hours, add 6 times the amount of water for the second and third times, and decoct for 1 hour; filter and combine the filtrates; concentrate the filtrates into extracts. The obtained extract is sprayed into the auxiliary material starch, sprayed and dried at an air inlet temperature of 70-160° C. and an outlet air temperature of 45-85° C. to obtain granules, compressed into tablets, and coated.

Embodiment 3

[0041] Take 200 grams of Artemisia argyi, 100 grams of Epimedium, 100 grams of Asparagus, 100 grams of Bupleurum, 100 grams of Toosendan, and 100 grams of Fritillaria. Put it into the extraction tank, add 8 times the amount of water to soak for 1 hour, then put the remaining four medicinal materials into it, add water to decoct three times, add 8 times the water for the first time, decoct for 1.5 hours, add 6 times for the second and third times respectively Measure the water and decoct for 1 hour; filter and combine the filtrates; concentrate the filtrates into extracts (each gram of extracts is equivalent to about 5 grams of the original drug). The obtained extract is sprayed into auxiliary material starch, sprayed and dried at an air inlet temperature of 70-160° C. and an outlet air temperature of 45-85° C. to obtain granules, compressed into tablets, and coated.

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Abstract

The invention discloses a pharmaceutical composition, which is prepared by extracting mugwort leaf, herba epimedii, radix asparagi, radix bupleuri, fructus toosendan and rhizoma bolbostemmae. A method for preparing the composition comprises the following steps: (1) mixing the Chinese traditional medicines, and decocting the mixture with water; (2) filtering the decoction and combining the filtrate; (3) concentrating the filtrate into an extract; and (4) adding an auxiliary material to the extract to prepare a proper preparation. The pharmaceutical composition produced by the method has the efficacies of soothing liver and qi stagnation and conditioning thoroughfare and conception vessels, is applied to treating symptoms of mastodynia, hyperplasia of mammary glands, and the like caused by liver depression and qi stagnation, and the syndrome of disharmony of the thoroughfare and conception vessels, and shows the improved curative effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating mammary gland hyperplasia and a preparation method thereof. Background technique [0002] Hyperplasia of the mammary glands is a non-inflammatory mass disease in the breast, which occurs mostly in middle-aged and middle-aged women, and the canceration rate is about 5%-10%. The clinical manifestations are characterized by lumps in one or both breasts, breast tenderness, pain aggravation before menstruation and relief after menstruation. In recent years, the incidence has a tendency to increase significantly. Therefore, the prevention and treatment of mammary gland hyperplasia is also one of the focuses of clinical research. [0003] Chronic cystic hyperplasia of mammary glands does not have a completely effective drug so far that can be completely treated. Some drugs can only improve or control local symptoms and signs. Treatment with weste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P15/14A61P17/00
Inventor 李华锋
Owner SHENZHEN SANSHUN PHARMA