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Quality control method of Xinnaokang capsule

A technology of preparation method and detection method, which is applied in the directions of capsule delivery, medical preparations containing active ingredients, measuring devices, etc., can solve the problems of non-conformity, unfavorable standardized production of drugs and improve production efficiency, and there is no quality control method for Xinnaokang capsules. and other issues to achieve the effect of ensuring safety and effectiveness and improving production efficiency

Active Publication Date: 2012-09-05
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, this standard does not have the quality control method of Xinnaokang Capsules, which will affect the quality and curative effect of the product, which is not conducive to the standardized production of drugs and the improvement of production efficiency, and does not conform to the trend of modern Chinese medicine development.

Method used

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  • Quality control method of Xinnaokang capsule
  • Quality control method of Xinnaokang capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Take the bulk drug of following weight parts:

[0047] 【Prescription】Salvia miltiorrhiza 40g, Radix Paeoniae Rubra 30g, Polygonum multiflorum 30g

[0048] Lycium barbarum 30g Pueraria 30g Chuanxiong 30g

[0049] Safflower 20g Alisma 30g Achyranthes 30g

[0050] Dilong 30g Curcuma 3g Polygala (Honey Roast) 30g

[0051] Jiujie calamus 30g Suanzaoren (stir-fried) 20g Deer heart powder 30g

[0052] Licorice 20g

[0053] [Preparation method] The above sixteen flavors, except deer heart powder, Chuanxiong, safflower, Alisma, Achyranthes bidentata, turmeric, polygala, calamus nine knots, wild jujube kernel, and licorice are crushed into fine powder and sieved. The other 6 flavors such as salvia miltiorrhiza, add water and decoct three times. For the first 3 hours, add 10 times the amount of water; for the second 2 hours, add 8 times the amount of water; , and the filtrate was concentrated into a paste. Add the above-mentioned fine ...

Embodiment 2

[0055] Take the bulk drug of following weight parts:

[0056] [Prescription] Salvia 40g, Radix Paeoniae Rubra 30g, Polygonum multiflorum 30g

[0057] Lycium barbarum 30g Pueraria 30g Chuanxiong 30g

[0058] Safflower 20g Alisma 30g Achyranthes 30g

[0059] Dilong 30g Curcuma 3g Polygala (Honey Roast) 30g

[0060] Jiujie calamus 30g Suanzaoren (stir-fried) 20g Deer heart powder 30g

[0061] Licorice 20g

[0062] [Preparation method] The above sixteen flavors, except deer heart powder, Chuanxiong, safflower, Alisma, Achyranthes bidentata, turmeric, polygala, calamus nine knots, wild jujube kernel, and licorice are crushed into fine powder and sieved. The other 6 flavors such as Salvia miltiorrhiza, add water and decoct three times. For the first 3 hours, add 8 times the amount of water; for the second time, add 6 times the amount of water; , and the filtrate was concentrated into a paste. Add the above-mentioned fine powder, mix, dry, pulverize,...

Embodiment 3-6

[0064] According to the same method and dosage as in Example 1, 4 batches of capsules of the present invention were produced in a pilot scale.

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Abstract

The invention discloses a quality control method of Xinnaokang capsule, which increases folium qualitative identification to Salvia miltiorrhiza and radix paeoniae rubrathe and also increases quantitative determination of content of paeoniflorin, thereby ensuring the security and effectiveness of the medicine, improving the product quality and being convenient for standard production of the medicine.

Description

technical field [0001] The invention relates to a quality control method of traditional Chinese medicine, in particular to a quality control method of Xinnaokang capsules. Background technique [0002] The prescription of Xinnaokang Capsules comes from page 47 of 13 volumes of traditional Chinese medicine preparations issued by the Ministry, and the standard number is WS3-B-2492-97. For coronary heart disease, angina pectoris and cerebral arteriosclerosis. The Xinnaokang Capsules are prescribed as follows: [0003] Salvia 80g Radix Paeoniae Rubra 60g Radix Polygoni Multiflori 60g [0004] Goji berry 60g Pueraria 60g Chuanxiong 60g [0005] Safflower 40g Alisma 60g Achyranthes 60g [0006] Dilong 60g Curcuma 6g Polygala (Honey Roast) 60g [0007] Jiujie calamus 60g Suanzaoren (stir-fried) 40g Deer heart powder 60g [0008] Licorice 40g [0009] The preparation method of the Xinnaokang Capsule is as follows: the above sixteen flavors, except deer heart powder, Chuanxion...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/48A61P9/10G01N30/36G01N30/90A61K35/34A61K35/64A61K35/62
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD