Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Prescription for curing type II diabetes and complications and preparation technology thereof

A technology for diabetes and complications, applied in the field of pharmaceutical preparations, can solve the problems of large toxic and side effects of western medicine ingredients, and achieve the effects of wide applicable population, large drug loading, and fast absorption.

Inactive Publication Date: 2009-12-02
孙民富
View PDF0 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, some compound preparations combined with traditional Chinese medicine for the treatment of diabetes have remarkable curative effects, but the western medicine ingredients contained in them have severe side effects, and type II diabetes is accompanied by ketosis, acidosis, liver and kidney insufficiency, heart failure, and respiratory failure. , acute myocardial infarction, severe infection and trauma, major surgery, and patients with clinical hypotension and hypoxia are not applicable

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Take 3.45 parts of gliclazide, 120 parts of astragalus, 100 parts of kudzu root, 40 parts of salvia

[0058] Add Pueraria root with 70% ethanol to reflux or heat extraction 3 times, the first time is 1.5 hours, the second time is 1 hour, the third time is 0.5 hours, filter, the filtrate is decompressed to recover ethanol, the extract is dried under reduced pressure, and crushed into powder; add astragalus and salvia miltiorrhiza to decoct for 2 to 3 times, each time for 1 hour, filter, combine the filtrate and concentrate under reduced pressure, and the obtained extracts are dried under reduced pressure and pulverized into powder; Chite, polyethylene glycol 4000 and 0.3% sodium carboxymethyl cellulose, mixed evenly, made into granules, and dried to obtain granules.

Embodiment 2

[0060] Take 3.45 parts of gliclazide, 120 parts of astragalus, 100 parts of kudzu root, 40 parts of salvia

[0061] Add Pueraria root with 70% ethanol to reflux or heat extraction 3 times, the first time is 1.5 hours, the second time is 1 hour, the third time is 0.5 hours, filter, the filtrate is decompressed to recover ethanol, the extract is dried under reduced pressure, and crushed into powder; add astragalus and salvia miltiorrhiza to decoct for 2 to 3 times, each time for 1 hour, filter, combine the filtrate and concentrate under reduced pressure, and the obtained extracts are dried under reduced pressure and pulverized into powder; Chite and an appropriate amount of polyethylene glycol 4000 are mixed evenly, made into granules, dried, added with 0.4% magnesium stearate, pressed into tablets or coated with film to obtain tablets.

Embodiment 3

[0063] Take 3.45 parts of gliclazide, 120 parts of astragalus, 100 parts of kudzu root, 40 parts of salvia

[0064]Add Pueraria root with 70% ethanol to reflux or heat extraction 3 times, the first time is 1.5 hours, the second time is 1 hour, the third time is 0.5 hours, filter, the filtrate is decompressed to recover ethanol, the extract is dried under reduced pressure, and crushed into powder; add astragalus and salvia miltiorrhiza to decoct for 2 to 3 times, each time for 1 hour, filter, combine the filtrate and concentrate under reduced pressure, the obtained extracts are dried under reduced pressure respectively, and pulverized into powder; Chite, polyethylene glycol 4000 and 0.1% sodium carboxymethylcellulose, mixed evenly, made into granules, dried, packed into capsules, and then filled into capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a prescription for curing type II diabetes and complications and a preparation technology thereof. The prescription for curing the type II diabetes is prepared by defining, quantifying, extracting, separating or manually synthesizing traditional Chinese medicinal materials, such as radix puerariae, radix astragali, red sage roots, and the like and adding a chemical medicine of gliclazide by a solid dispersion technology. The prescription for curing the type II diabetes is a compound preparation by compounding Chinese and Western medicines and chemical medicines, can be prepared into preparation formulations of tablets, granules, capsules, dripping pills, and the like, can effectively cure the type II diabetes, improves the body immunity and can effectively delay the occurrence and the development of the diabetes complications. The preparation technology of the compound preparation has short technological flow, low production cost, rapid effectual action, unique prescription and preparation method thereof and remarkable treatment effect.

Description

Technical field [0001] The invention is a new prescription combining traditional Chinese and western medicine composed of traditional Chinese medicinal materials and chemical medicines for treating type II diabetes and its preparation process. It is made by qualitatively and quantitatively extracting, separating, or artificially synthesizing the active ingredients in Chinese medicinal materials such as kudzu root, astragalus, and salvia miltiorrhiza, and then adding the chemical drug gliclazide. It is developed by solid dispersion technology and has a significant hypoglycemic effect. It can effectively improve human immunity, inhibit and effectively treat complications of diabetes. It belongs to the field of pharmaceutical preparations. Background technique [0002] Diabetes is a group of clinical syndromes caused by the interaction of genetic and environmental factors. Absolute or relative insufficiency of insulin secretion and decreased sensitivity of target tissue cells...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/537A61K36/57A61K36/605A61K36/804A61K36/815A61K36/8945A61K36/8964A61K36/899A61P3/10A61K31/403
Inventor 孙民富
Owner 孙民富
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com