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Formulation of small RNA/DNA whitening product and preparation method thereof

A product and whitening technology, applied in the field of skin whitening, can solve problems such as reduced expression level, achieve the effect of small dosage, skin protection and quick effect

Inactive Publication Date: 2009-12-16
JIANGSU GENECON BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Significantly reduces the expression level of genes related to melanin formation but is different from related gene defects or deletions in albinism

Method used

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  • Formulation of small RNA/DNA whitening product and preparation method thereof
  • Formulation of small RNA/DNA whitening product and preparation method thereof
  • Formulation of small RNA/DNA whitening product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] The following is an example of a simple formula of Gene Whitening Lotion

[0116] 1 Double-stranded oligonucleotide 150μg

[0117] Loinase

[0118] p-protein

[0119] Melanocortin-1 receptor

[0120] Kinesin

[0121] 2 cationic phospholipids 1.7%

[0122] 3 Ethanol 10ml

[0123] 4 cholesterol 0.3%

[0124] 5Vitamine A and E 1%

[0125] 8 glycerol 5%

[0126] 9 spices

[0127] 10 add ion-free double distilled water to a total of 100ml

Embodiment 2

[0129] The following is an example of the simple formula of Gene Whitening Lotion Type II

[0130] 1Single-stranded oligonucleotide 200μg

[0131] Loinase

[0132] p-protein

[0133] Loinase-related protein type 1

[0134] Melanocortin-1 receptor

[0135] AIM-1 protein

[0136] 2 Hyaluronic acid 2%

[0137] 6Vitamine C 1%

[0138] 7Vitamine E 1%

[0139] 6 glycerol 5%

[0140] 7 spices a little

[0141] 8 peptide 0.002%

[0142] 9 add ion-free double distilled water to a total of 100ml

Embodiment 3

[0144] The following is an example of a compound gene skin whitening lotion formula

[0145] ·Ion-free double distilled water about 70ml

[0146] ·Double-stranded oligonucleotide 100μg

[0147] ·Ascorbic acid 3%

[0148] ·Timeng acid 2%

[0149] ·Lactic acid 2%

[0150] ·Kojic acid 2%

[0151] ·Ethanol 10ml

[0152] ·Arbutin 1%

[0153] · Phospholipids 1.7%

[0154] ·Cholesterol 0.3%

[0155] ·Glycerin 3%

[0156] ·Urea 1%

[0157] ·Vitamine A and E 1%

[0158] ·FURILDIOXIME OR PENICILLAMINE 1%

[0159] ·Total 100ml

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Abstract

The invention relates to a small RNA / DNA whitening product series, which mainly consists of a small RNA skin whitening lotion and a small RNA skin beauty cream. The small RNA skin whitening lotion mainly comprises efficient active ingredients for removing skin pigmentation and whitening skin, such as nano single-strand or double-strand oligonucleotides for specially and efficiency restraining genes (Asip, Mclr, Mitf, Dct, Silv, Oca2, Myo5a, Loc51151, Rab27a, Pomc, OA1,F2rl1, Kinesin, Slc24a5, Tyr and Tyrp1) relevant to melanin generation and a transdermal agent for stimulating oligonucleotides to enter skin melanocytes; the small RNA skin beauty cream comprises a plurality of highly active materials for maintaining pure and white skin and small RNA segments to prevent the sunshine from damaging the protective components of the skin and remove free radicals, and anti-aging and anti-inflammatory effective molecules. In addition, the invention further provides a formulation, a method and a procedure for preparing the series of whitening products.

Description

1 technical field [0001] The field of the present invention is skin whitening. To be precise, the present invention puts forward the concept of true small RNA / DNA whitening products, and designs novel small RNA fragments for skin whitening and formulas, methods and processes for manufacturing small RNA whitening products. 2 background technology [0002] market background [0003] The love of beauty is common to everyone. As the saying goes: One white hides one hundred ugliness, especially for oriental women, having white and tender skin is a dream desire. Skin color is determined innately. At present, most of the so-called whitening cosmetics on the market only have the function of covering or bleaching, and they only treat the symptoms rather than the root cause. With the development of biotechnology, especially after scientists from all over the world have teamed up to complete the sequencing of all human genes, scientists have discovered a new method that can be used to inhib...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K8/67A61K8/64A61Q19/02A61Q19/08
Inventor 殷勤伟黄兵
Owner JIANGSU GENECON BIOLOGICAL TECH
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