Direct contact type cell co-culture device

Abstract

The invention relates to a direct contact type cell co-culture device which belongs to the technical field of cell co-culture devices. The direct contact type cell co-culture device comprises a culture hole, a culture plate and an upper cover, wherein the culture hole is arranged on the culture plate, and the upper cover is covered on the culture plate and seals the culture hole; an isolation plate is arranged in the culture hole, and the culture hole is divided into a plurality of small culture chambers. A reverse hook is arranged on the outer side wall of the upper part of the culture hole, two upright edges of the isolation plate are installed in a side fixing groove arranged in the culture hole, the bottom edge of the isolation plate is provided with an elastic pad, and the elastic pad is pressed on the bottom surface of the culture hole; when the culture hole is not pressed, the height of the isolation plate is slightly higher than the depth of the culture hole, and the upper edge of the isolation plate is installed in an upper fixing groove; and the end of the upper fixing groove is provided with a connecting line with a circular ring. Before being unsealed, the absolutely aseptic state of the cell culture device can be ensured. The invention has the advantages of simple operation and reliable effect, can clearly observe and contrast the situation of the growth change of cells at the edges of the small culture chambers, can realize the co-culture of various cells and does not influence the normal adherence and multiplication of the cells.

Description

technical field [0001] The invention relates to a direct contact cell co-culture device, which belongs to the technical field of cell co-culture devices. Background of the invention: [0002] Putting different cells in the same environment for co-cultivation, through the study of the interaction and transformation between cells, is more and more used in the field of medical research. Cell co-culture is mainly divided into direct contact co-culture and non-direct contact co-culture. However, the currently commonly used cell co-culture devices need to use expensive Matrix gel (Matrix gel) and Transwell culture chambers in combination, which can only carry out indirect contact co-cultivation between two types of cells, and cannot achieve direct cell contact co-cultivation. Due to the current requirements of cell co-culture research, it is urgent to develop a direct contact cell co-culture device. Invention content: [0003] Aiming at the shortcomings of existing cell co-cul...

AI Technical Summary

Problems solved by technology

However, the currently commonly used cell co-culture devices need to use expensive Matrix gel (Matrix gel) and Transwell culture chambers in combination, which can only carry out indirect contact co-cultivation between two types of cells, and cannot achieve direct cell contact co-cultivation. The requirements of current cell co-culture research, so it is urgent to develop a direct contact cell co-culture device

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